Penicillins - Pharmacology
Research News and Information

Sunday, November 22, 2009

Outer membrane porin M35 of Moraxella catarrhalis mediates susceptibility to aminopenicillins.

2 Sep 2009 BACKGROUND: The outer membrane protein M35 is a conserved porin of type 1 strains of the respiratory pathogen Moraxella catarrhalis. It was previously shown that M35 is involved in the uptake of essential nutrients required for bacterial growth and ... Read more...

An extracytoplasmic function sigma factor controls beta-lactamase gene expression in Bacillus anthracis and other Bacillus cereus group species.

26 Aug 2009 The susceptibility of most Bacillus anthracis strains to beta-lactam antibiotics is intriguing considering that the closely related species Bacillus cereus and Bacillus thuringiensis typically produce beta-lactamases and the B. anthracis genome ... Read more...

Antibiotic resistance in Latin America: a cause for alarm.

19 Jun 2009 The burden of pneumococcal disease in Latin America is most pronounced in children aged <6 years. The increasing rate of resistance of Streptococcus pneumoniae to penicillin and other antibiotics has generated concern among health authorities, since ... Read more...

Latest indexed articles for 'Penicillins - Pharmacology'

These are the very latest articles for this heading:

• Outer membrane porin M35 of Moraxella catarrhalis mediates susceptibility to aminopenicillins. 2 Sep 2009
• An extracytoplasmic function sigma factor controls beta-lactamase gene expression in Bacillus anthracis and other Bacillus cereus group species. 26 Aug 2009
• Antibiotic resistance in Latin America: a cause for alarm. 19 Jun 2009
• Antimicrobial resistance among isolates causing invasive pneumococcal disease before and after licensure of heptavalent conjugate pneumococcal vaccine. 16 Jun 2009
• Clinical efficacy of temocillin. 9 Jun 2009
• Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. 6 Jun 2009
• The highly conserved serine threonine kinase StkP of Streptococcus pneumoniae contributes to penicillin susceptibility independently from genes encoding penicillin-binding proteins. 3 Jun 2009
• Comparative genome analysis of high-level penicillin resistance in Streptococcus pneumoniae. 30 May 2009
• Human health risk assessment of penicillin/aminopenicillin resistance in enterococci due to penicillin use in food animals. 30 May 2009
• Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance. 30 May 2009
• Imcroporin, a new cationic antimicrobial peptide from the venom of the scorpion Isometrus maculates. 16 May 2009
• [Improvement of methods for identification of atypical anthrax strains and their differentiation from closely related bacilli] 29 Apr 2009
• The efficacy of high-dose penicillin for community-acquired pneumonia diagnosed by pneumococcal urine antigen test. 23 Apr 2009
• Serotypes and antimicrobial susceptibilities of invasive Streptococcus pneumoniae pre- and post-seven valent pneumococcal conjugate vaccine introduction in Alberta, Canada, 2000-2006. 16 Apr 2009
• Robust experimental design for optimizing the microbial inhibitor test for penicillin detection in milk. 15 Apr 2009
• [Diversity analysis of anaerobic fungi in the co-cultures with or without methanogens by amplified ribosomal intergenic spacer analysis] 2 Apr 2009
• Extraction and analysis of chemical modification patterns in drug development. 30 Mar 2009
• Single-copy chromosomal integration systems for Francisella tularensis. 30 Mar 2009
• Management of antibiotic-resistant Streptococcus pneumoniae infections and the use of pneumococcal conjugate vaccines. 30 Mar 2009
• In vitro inferiority of ceftazidime compared with other beta-lactams for viridans group Streptococcus bacteremia in pediatric oncology patients: implications for antibiotic choices. 30 Mar 2009

See a longer list of these articles.

Technical information about 'Penicillins'

Definition: A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)

Registry Number: 0

Descriptor UI: D010406

Alternative terms: Penicillins; Antibiotics, Penicillin; Penicillin Antibiotics; Penicillin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.065.589.099.750; D02.886.108.750; D03.438.260.825; D03.605.084.737; D04.075.080.875.099.221.750;

Online Note: use PENICILLINS to search PENICILLIN 1966-74 & HETACILLIN 1974-84

History Note: 75; was PENICILLIN 1963-74; /adv eff-pois-tox was PENICILLIN TOXICOLOGY 1963-65; HETACILLIN was heading 1974-84

Technical Notes: check text for a specific if possible