Penicillins
Research News and Information

Sunday, November 22, 2009

Pathogenesis, treatment, and prevention of pneumococcal pneumonia.

29 Oct 2009 Pneumococcus remains the most common cause of community-acquired pneumonia worldwide. Streptococcus pneumoniae is well adapted to people, and is a frequent inhabitant of the upper airways in healthy hosts. This seemingly innocuous state of ... Read more...

Incidence of invasive pneumococcal disease among children after introduction of a 7-valent pneumococcal conjugate vaccine: a population-based study in Olmsted County, Minnesota.

29 Sep 2009 OBJECTIVE: To examine the effect of the 7-valent pneumococcal conjugate vaccine in a well-characterized population in Olmsted County, Minnesota, with a combination of urban and rural residents likely to have a relatively low risk of invasive ... Read more...

Outer membrane porin M35 of Moraxella catarrhalis mediates susceptibility to aminopenicillins.

2 Sep 2009 BACKGROUND: The outer membrane protein M35 is a conserved porin of type 1 strains of the respiratory pathogen Moraxella catarrhalis. It was previously shown that M35 is involved in the uptake of essential nutrients required for bacterial growth and ... Read more...

Latest indexed articles for 'Penicillins'

These are the very latest articles for this heading:

• Pathogenesis, treatment, and prevention of pneumococcal pneumonia. 29 Oct 2009
• Incidence of invasive pneumococcal disease among children after introduction of a 7-valent pneumococcal conjugate vaccine: a population-based study in Olmsted County, Minnesota. 29 Sep 2009
• Outer membrane porin M35 of Moraxella catarrhalis mediates susceptibility to aminopenicillins. 2 Sep 2009
• Infections caused by Gram-positive bacteria: a review of the global challenge. 30 Aug 2009
• An extracytoplasmic function sigma factor controls beta-lactamase gene expression in Bacillus anthracis and other Bacillus cereus group species. 26 Aug 2009
• Syphilitic perioptic neuritis mimicking papilloedema. 15 Aug 2009
• [Bilateral panuveitis with papillary swelling] 30 Jul 2009
• Intrapartum antibiotics for known maternal Group B streptococcal colonization. 6 Jul 2009
• Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme. 5 Jul 2009
• [Acute poststreptoccocal chorea: an atypical postoperative reaction following cardiac surgery for mitral valvulopathy] 2 Jul 2009
• Determination of penicillins in milk using LC-UV, LC-MS and LC-MS/MS. 29 Jun 2009
• Feasibility of one-stop antenatal syphilis screening in Ulaanbaatar, Mongolia: women and providers perspectives. 29 Jun 2009
• [A sudden redness and swelling of the face] 29 Jun 2009
• Progressive rash after recent antibiotic exposure. 26 Jun 2009
• The role of nitric oxide in the inhibitory effect of ghrelin against penicillin-induced epileptiform activity in rat. 21 Jun 2009
• Antibiotic resistance in Latin America: a cause for alarm. 19 Jun 2009
• Antimicrobial resistance among isolates causing invasive pneumococcal disease before and after licensure of heptavalent conjugate pneumococcal vaccine. 16 Jun 2009
• Penicillin/ampicillin efficacy among children with severe pneumonia due to penicillin-resistant pneumococcus (MIC=4 microg ml(-1)). 16 Jun 2009
• Collagen-gentamicin implant for prevention of sternal wound infection; long-term follow-up of effectiveness. 16 Jun 2009
• Clinical efficacy of temocillin. 9 Jun 2009

See a longer list of these articles.

Technical information about 'Penicillins'

Definition: A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)

Registry Number: 0

Descriptor UI: D010406

Alternative terms: Penicillins; Antibiotics, Penicillin; Penicillin Antibiotics; Penicillin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.065.589.099.750; D02.886.108.750; D03.438.260.825; D03.605.084.737; D04.075.080.875.099.221.750;

Online Note: use PENICILLINS to search PENICILLIN 1966-74 & HETACILLIN 1974-84

History Note: 75; was PENICILLIN 1963-74; /adv eff-pois-tox was PENICILLIN TOXICOLOGY 1963-65; HETACILLIN was heading 1974-84

Technical Notes: check text for a specific if possible