Peptide Fragments
Research News and Information

Saturday, November 21, 2009

High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients.

6 Dec 2009 The main objective of this study was to determine whether elevated blood beta-amyloid (Abeta) levels among the first-degree relatives of patients with Alzheimer's Disease (AD) are associated with vascular risk factors of AD. Serum Abeta was measured ... Read more...

Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy.

29 Nov 2009 Transforming growth factor-beta (TGF-beta) is a cytokine with potent immunosuppressive effects and is overexpressed in many tumors. Therefore, development of molecules able to inhibit TGF-beta is of paramount importance to improve the efficacy of ... Read more...

The second Cu(II)-binding site in a proton-rich environment interferes with the aggregation of amyloid-beta(1-40) into amyloid fibrils.

15 Nov 2009 The overall morphology and Cu(II) ion coordination for the aggregated amyloid-beta(1-40) [Abeta(1-40)] in N-ethylmorpholine (NEM) buffer are affected by Cu(II) ion concentration. This effect is investigated by transmission electron microscopy (TEM), ... Read more...

Latest indexed articles for 'Peptide Fragments'

These are the very latest articles for this heading:

• High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients. 6 Dec 2009
• Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy. 29 Nov 2009
• The second Cu(II)-binding site in a proton-rich environment interferes with the aggregation of amyloid-beta(1-40) into amyloid fibrils. 15 Nov 2009
• The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. 13 Nov 2009
• Solution structure and functional characterization of human plasminogen kringle 5. Nov 2009
• TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo. 30 Oct 2009
• Invited commentary. 30 Oct 2009
• Plasma amyloid beta42 and amyloid beta40 levels are associated with early cognitive dysfunction after cardiac surgery. 30 Oct 2009
• The interrelationship between preoperative anemia and N-terminal pro-B-type natriuretic peptide: the effect on predicting postoperative cardiac outcome in vascular surgery patients. 30 Oct 2009
• A randomized clinical trial investigating the relationship between aprotinin and hypercoagulability in off-pump coronary surgery. 30 Oct 2009
• Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial. 30 Oct 2009
• DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model. 26 Oct 2009
• Pre-operative cardiac risk assessment in noncardiac surgery: are natriuretic peptides the magic bullet? 18 Oct 2009
• Is a pre-operative brain natriuretic peptide or N-terminal pro-B-type natriuretic peptide measurement an independent predictor of adverse cardiovascular outcomes within 30 days of noncardiac surgery? A systematic review and meta-analysis of observational studies. 18 Oct 2009
• Structural insights into glucan phosphatase dynamics using amide hydrogen-deuterium exchange mass spectrometry. 18 Oct 2009
• Thermodynamic characterization of the interaction between the C-terminal domain of extracellular superoxide dismutase and heparin by isothermal titration calorimetry. 18 Oct 2009
• Novel binding motif of ACTH analogues at the melanocortin receptors. 18 Oct 2009
• Characterization of the CHK1 allosteric inhibitor binding site. 18 Oct 2009
• The stathmin-derived I19L peptide interacts with FtsZ and alters its bundling. 18 Oct 2009
• The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse. 14 Oct 2009

See a longer list of these articles.

Technical information about 'Peptide Fragments'

Definition: Partial proteins formed by partial hydrolysis of complete proteins.

Registry Number: 0

Descriptor UI: D010446

Alternative terms: Peptide Fragments; Fragments, Peptide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; ultrastructure;

Tree Number: D12.644.541;

History Note: 74