Pharmaceutical Preparations
Research News and Information

Saturday, November 21, 2009

Subarachnoid hemorrhage and the distribution of drugs delivered into the cerebrospinal fluid. Laboratory investigation.

30 Oct 2009 OBJECT: Investigators in experimental and clinical studies have used the intrathecal route to deliver drugs to prevent or treat vasospasm. However, a clot near an artery or arteries after subarachnoid hemorrhage (SAH) may hamper distribution and ... Read more...

Challenges in developing evidence-based drug dosing guidelines for adults and children receiving renal replacement therapy.

30 Oct 2009 The challenges of appropriate drug dosing in patients with renal failure requiring renal replacement therapy (RRT) have been exacerbated by recent trends in both RRT technology and practices. Nearly all these changes have resulted in augmented drug ... Read more...

When to conduct a renal impairment study during drug development: US Food and Drug Administration perspective.

30 Oct 2009 To optimize drug therapy for individuals, it is critical to understand how various intrinsic (e.g., age, gender, race, genetics, organ impairment) and extrinsic factors (e.g., diet, smoking, concomitantly administered drugs) affect drug exposure and ... Read more...

Latest indexed articles for 'Pharmaceutical Preparations'

These are the very latest articles for this heading:

• Subarachnoid hemorrhage and the distribution of drugs delivered into the cerebrospinal fluid. Laboratory investigation. 30 Oct 2009
• Patent watch. Drug metabolite claims are patentable. 30 Oct 2009
• Challenges in developing evidence-based drug dosing guidelines for adults and children receiving renal replacement therapy. 30 Oct 2009
• When to conduct a renal impairment study during drug development: US Food and Drug Administration perspective. 30 Oct 2009
• How a US regulator can encourage new science. 30 Oct 2009
• Continuing the use of the Cockcroft-Gault equation for drug dosing in patients with impaired renal function. 30 Oct 2009
• Use of the MDRD study equation to estimate kidney function for drug dosing. 30 Oct 2009
• Nephropharmacology: drugs and the kidney. 30 Oct 2009
• Epidemiologic evaluation of pharmaceuticals with limited evidence of carcinogenicity. 30 Oct 2009
• Going off-label without venturing off-course: evidence and ethical off-label prescribing. 24 Oct 2009
• Hyperkalaemia. 21 Oct 2009
• Intellectual property. Balancing innovation and access: patent challenges tip the scales. 14 Oct 2009
• Drug shortages and public health. 13 Oct 2009
• Fate and removal of pharmaceuticals and illicit drugs in conventional and membrane bioreactor wastewater treatment plants and by riverbank filtration. 11 Oct 2009
• Practical overview of analytical methods for endocrine-disrupting compounds, pharmaceuticals and personal care products in water and wastewater. 11 Oct 2009
• The cost of donated drugs. 30 Sep 2009
• Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem. 29 Sep 2009
• Liver tissue engineering in the evaluation of drug safety. 29 Sep 2009
• Identification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion. 29 Sep 2009
• Prevalence of fatal adverse drug reactions in hospitalized patients. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Pharmaceutical Preparations'

Definition: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.

Registry Number: 0

Descriptor UI: D004364

Alternative terms: Pharmaceutical Preparations; Preparations, Pharmaceutical; Drugs; Pharmaceutic Preparations; Preparations, Pharmaceutic;

Related Mesh Headings: Pharmacology; Plants, Medicinal; Receptors, Drug;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; radiation effects; standards; supply & distribution; chemistry; contraindications; blood; cerebrospinal fluid; urine;

Tree Number: D26;

History Note: 98(63)

Technical Notes: GEN & unspecified only; /adv eff permitted but consider DRUG THERAPY /adv eff; drug names: use NOMENCLATURE; policy: Manual section 25; metab detoxication of drugs = METABOLIC DETOXICATION, DRUG;