Phenylalanine - Blood
Research News and Information

Monday, November 23, 2009

Long-term efficacy of 'ready-to-drink' protein substitute in phenylketonuria.

29 Sep 2009 BACKGROUND: In phenylketonuria (PKU), protein substitute is an essential part of dietary treatment. Short-term studies have demonstrated that liquid protein substitutes (LPS) are efficacious, and improve compliance in teenagers and adults with PKU, ... Read more...

Sapropterin: a new therapeutic agent for phenylketonuria.

2 Aug 2009 OBJECTIVE: To summarize the role of pharmacotherapy in the management of phenylketonuria (PKU) and to review the pharmacology, pharmacokinetics, pharmacodynamics, efficacy data, and safety profile of sapropterin for this indication. DATA SOURCES: A ... Read more...

Metabolic phenotypes of phenylketonuria. Kinetic and molecular evaluation of the Blaskovics protein loading test.

14 Jul 2009 BACKGROUND: As part of the German Collaborative Study of Children Treated for Phenylketonuria (PKU), a three-day protein loading test was applied to children at 6 months of age. This load elicits three principal types of blood phenylalanine (Phe) ... Read more...

Latest indexed articles for 'Phenylalanine - Blood'

These are the very latest articles for this heading:

• Long-term efficacy of 'ready-to-drink' protein substitute in phenylketonuria. 29 Sep 2009
• Sapropterin: a new therapeutic agent for phenylketonuria. 2 Aug 2009
• In response to van Spronsen et al (2009) phenylalanine tolerance can already reliably be assessed at the age of 2 years in patients with PKU (J Inherit Metab Dis 32: 27-31). 30 Jul 2009
• Serum phenylalanine concentrations in patients post trauma and burn correlate to neopterin concentrations. 30 Jul 2009
• Metabolic phenotypes of phenylketonuria. Kinetic and molecular evaluation of the Blaskovics protein loading test. 14 Jul 2009
• Neonatal screening for congenital hypothyroidism and phenylketonuria in China. 7 Jul 2009
• Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. 7 Jul 2009
• Measurement of protein fractional synthesis and breakdown rates in the skin of rabbits using a subflooding dose method. 16 Jun 2009
• Blood phenylalanine concentrations in patients with PAH-deficient hyperphenylalaninaemia off diet without and with three different single oral doses of tetrahydrobiopterin: assessing responsiveness in a model of statistical process control. 8 Jun 2009
• A simple and rapid method for measurement of (10)B-para-boronophenylalanine in the blood for boron neutron capture therapy using fluorescence spectrophotometry. 7 Jun 2009
• Determination of phenylalanine in blood by high-performance anion-exchange chromatography-pulsed amperometric detection to diagnose phenylketonuria. 5 Jun 2009
• Adults with late diagnosed PKU and severe challenging behaviour. 30 May 2009
• Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein. 25 May 2009
• Effects of L-histidine depletion and L-tyrosine/L-phenylalanine depletion on sensory and motor processes in healthy volunteers. 29 Apr 2009
• Dietary management practices in phenylketonuria across European centres. 8 Apr 2009
• Assessment of mitochondrial respiratory chain function in hyperphenylalaninaemia. 11 Mar 2009
• Acrodermatitis enteropathica-like eruption in metabolic disorders: acrodermatitis dysmetabolica is proposed as a better term. 9 Mar 2009
• Efficacy of sapropterin dihydrochloride in increasing phenylalanine tolerance in children with phenylketonuria: a phase III, randomized, double-blind, placebo-controlled study. 2 Mar 2009
• Aromatic amino acids in weight-recovered females with anorexia nervosa. 27 Feb 2009
• Omega-3 LC-PUFA supply and neurological outcomes in children with phenylketonuria (PKU). 27 Feb 2009

See a longer list of these articles.

Technical information about 'Phenylalanine'

Definition: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.

Chemical name: L-Phenylalanine

Registry Number: 63-91-2

Descriptor UI: D010649

Alternative terms: Phenylalanine; Phenylalanine, L-Isomer; L-Isomer Phenylalanine; Phenylalanine, L Isomer; L-Phenylalanine; Endorphenyl;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.125.072.050.685; D12.125.142.666;