Phenylalanine
Research News and Information

Sunday, November 22, 2009

Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy.

18 Oct 2009 In sickle cell hemoglobin, individual tetramers associate into long fibers as a consequence of the mutation at the beta6 position. In this study UV resonance Raman spectroscopy is used to monitor the formation of Hb S fibers in real time through ... Read more...

Aza-beta3-cyclopeptides: a new way of controlling nitrogen chirality.

12 Oct 2009 Sixteen and 24 membered aza-beta(3)-peptidic macrocycles containing a alpha-hydrazinoacid or a beta(3)-aminoacid were synthesized. The conformation of these pseudopeptides was determined by using NH chemical shift analysis, NH extinction, VT-NMR ... Read more...

Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator.

12 Oct 2009 Protein-protein interactions play an essential role in cellular function, and methods to discover and characterize them in their native context are of paramount importance for gaining a deeper understanding of biological networks. In this study, an ... Read more...

Latest indexed articles for 'Phenylalanine'

These are the very latest articles for this heading:

• Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy. 18 Oct 2009
• Aza-beta3-cyclopeptides: a new way of controlling nitrogen chirality. 12 Oct 2009
• Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator. 12 Oct 2009
• Long-term efficacy of 'ready-to-drink' protein substitute in phenylketonuria. 29 Sep 2009
• Biodistribution of (10)B for Boron Neutron Capture Therapy (BNCT) in a mouse model after injection of sodium mercaptoundecahydro-closo-dodecaborate and l-para-boronophenylalanine. 29 Sep 2009
• Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population. 29 Sep 2009
• Bioproduction of the aroma compound 2-phenylethanol in a solid-liquid two-phase partitioning bioreactor system by Kluyveromyces marxianus. 29 Sep 2009
• The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity. 23 Sep 2009
• The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues. 22 Sep 2009
• Structural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutations. 8 Sep 2009
• Large-scale movement of functional domains facilitates aminoacylation by human mitochondrial phenylalanyl-tRNA synthetase. 4 Sep 2009
• Controlled release from modified amino acid hydrogels governed by molecular size or network dynamics. 30 Aug 2009
• A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. 30 Aug 2009
• Substrate binding site flexibility of the small heat shock protein molecular chaperones. 24 Aug 2009
• Aromatic interactions promote self-association of collagen triple-helical peptides to higher-order structures. 23 Aug 2009
• Pyridoxal 5'-phosphate binding in lysine-modified PAMAM dendrimers: a biomimetic approach. 18 Aug 2009
• Fmoc-diphenylalanine self-assembly mechanism induces apparent pKa shifts. 16 Aug 2009
• Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli. 16 Aug 2009
• Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity. 15 Aug 2009
• Anti-adhesive coating and clearance of device associated uropathogenic Escherichia coli cystitis. 13 Aug 2009

See a longer list of these articles.

Technical information about 'Phenylalanine'

Definition: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.

Chemical name: L-Phenylalanine

Registry Number: 63-91-2

Descriptor UI: D010649

Alternative terms: Phenylalanine; Phenylalanine, L-Isomer; L-Isomer Phenylalanine; Phenylalanine, L Isomer; L-Phenylalanine; Endorphenyl;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.125.072.050.685; D12.125.142.666;