Phosphopyruvate Hydratase - Metabolism
Research News and Information

Saturday, November 21, 2009

Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism.

21 Sep 2009 Enolase enzymes are abundantly expressed, cytosolic carbon-oxygen lyases known for their role in glucose metabolism. Recently, enolase has been shown to possess a variety of different regulatory functions, beyond glycolysis and gluconeogenesis, ... Read more...

The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice.

14 Sep 2009 Granulocyte-colony stimulating factor (G-CSF) is a hematopoietic growth factor that controls proliferation and differentiation of neural stem cells. Although recent studies have begun to explore G-CSF-related mechanisms of action in various disease ... Read more...

Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model.

30 Aug 2009 OBJECTIVE: Innovations in pediatric cardiovascular surgery have resulted in significant improvements in survival for children with congenital heart disease. In adults with such disease, however, surgical morbidity and mortality remain significant. ... Read more...

Latest indexed articles for 'Phosphopyruvate Hydratase - Metabolism'

These are the very latest articles for this heading:

• Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism. 21 Sep 2009
• The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice. 14 Sep 2009
• Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model. 30 Aug 2009
• Exposure of HL-60 human leukaemic cells to 4-hydroxynonenal promotes the formation of adduct(s) with alpha-enolase devoid of plasminogen binding activity. 11 Aug 2009
• Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity. 30 Jul 2009
• Temporal lobe sclerosis associated with hippocampal sclerosis in temporal lobe epilepsy: neuropathological features. 30 Jul 2009
• An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen. 30 Jul 2009
• Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model. 16 Jul 2009
• Characterization of protein impurities and site-specific modifications using peptide mapping with liquid chromatography and data independent acquisition mass spectrometry. 13 Jul 2009
• Extracorporeal shock-wave therapy enhanced wound healing via increasing topical blood perfusion and tissue regeneration in a rat model of STZ-induced diabetes. 29 Jun 2009
• Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. 29 Jun 2009
• Mild to moderate early exercise promotes recovery from cerebral ischemia in rats. 29 Jun 2009
• Neuron-specific RNA interference using lentiviral vectors. 29 Jun 2009
• Reelin and Notch1 cooperate in the development of the dentate gyrus. 29 Jun 2009
• Neurobehavioral performance in feline immunodeficiency virus infection: integrated analysis of viral burden, neuroinflammation, and neuronal injury in cortex. 29 Jun 2009
• Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma. 27 Jun 2009
• Acanthamoeba castellanii: proteins involved in actin dynamics, glycolysis, and proteolysis are regulated during encystation. 8 Jun 2009
• The central nucleus of the amygdala and corticotropin-releasing factor: insights into contextual fear memory. Jun 2009
• OmpA is the critical component for Escherichia coli invasion-induced astrocyte activation. 30 May 2009
• Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury. 30 May 2009

See a longer list of these articles.

Technical information about 'Phosphopyruvate Hydratase'

Definition: A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity.

Chemical name: 2-Phospho-D-glycerate hydro-lyase

Registry Number: EC 4.2.1.11

Descriptor UI: D010751

Alternative terms: Phosphopyruvate Hydratase; Hydratase, Phosphopyruvate; 2-Phospho-D-Glycerate Hydrolase; 2 Phospho D Glycerate Hydrolase; Enolase; 2-Phospho-D-Glycerate Hydro-Lyase; 2 Phospho D Glycerate Hydro Lyase; Hydro-Lyase, 2-Phospho-D-Glycerate; 2-Phosphoglycerate Dehydratase; 2 Phosphoglycerate Dehydratase; Dehydratase, 2-Phosphoglycerate; beta-Enolase; beta Enolase; Muscle-Specific Enolase; Enolase, Muscle-Specific; Muscle Specific Enolase; Enolase 3; gamma-Enolase; gamma Enolase; Nervous System-Specific Enolase; Enolase, Nervous System-Specific; Nervous System Specific Enolase; System-Specific Enolase, Nervous; Neuron-Specific Enolase; Enolase, Neuron-Specific; Neuron Specific Enolase; Enolase 2; alpha-Enolase; alpha Enolase; Non-Neuronal Enolase; Enolase, Non-Neuronal; Non Neuronal Enolase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.520.241.300.500;

History Note: 73(64)