Phosphopyruvate Hydratase
Research News and Information

Saturday, November 21, 2009

Streptococcus suis enolase functions as a protective antigen displayed on the bacterial cell surface.

13 Nov 2009 BACKGROUND: Streptococcus suis serotype 2 (SS2) has evolved into a highly infectious entity, posing a great threat to public health. Screening for and identification of protective antigens plays an important role in developing therapies against SS2 ... Read more...

Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury.

29 Sep 2009 OBJECT: During recent years, several biomarkers have been introduced for use in the diagnosis of traumatic brain injury (TBI). The primary objective of this investigation was to determine if S100B (or S100 calcium-binding protein B) and ... Read more...

Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism.

21 Sep 2009 Enolase enzymes are abundantly expressed, cytosolic carbon-oxygen lyases known for their role in glucose metabolism. Recently, enolase has been shown to possess a variety of different regulatory functions, beyond glycolysis and gluconeogenesis, ... Read more...

Latest indexed articles for 'Phosphopyruvate Hydratase'

These are the very latest articles for this heading:

• Streptococcus suis enolase functions as a protective antigen displayed on the bacterial cell surface. 13 Nov 2009
• Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury. 29 Sep 2009
• Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism. 21 Sep 2009
• The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice. 14 Sep 2009
• Serum concentrations of s100b and NSE in migraine. 7 Sep 2009
• Elevated serum S100B protein and neuron-specific enolase levels in carbon monoxide poisoning. 30 Aug 2009
• Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model. 30 Aug 2009
• Exposure of HL-60 human leukaemic cells to 4-hydroxynonenal promotes the formation of adduct(s) with alpha-enolase devoid of plasminogen binding activity. 11 Aug 2009
• Stem cells modified by brain-derived neurotrophic factor to promote stem cells differentiation into neurons and enhance neuromotor function after brain injury. 30 Jul 2009
• Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity. 30 Jul 2009
• Temporal lobe sclerosis associated with hippocampal sclerosis in temporal lobe epilepsy: neuropathological features. 30 Jul 2009
• An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen. 30 Jul 2009
• Plasmodium falciparum enolase: stage-specific expression and sub-cellular localization. 28 Jul 2009
• Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model. 16 Jul 2009
• Characterization of protein impurities and site-specific modifications using peptide mapping with liquid chromatography and data independent acquisition mass spectrometry. 13 Jul 2009
• Granular cell tumor of the cecum with extensive hyalinization and calcification: a case report. 12 Jul 2009
• Validating serologic biomarkers of brain injury for cardiac arrest research. 29 Jun 2009
• Neuron-specific enolase and S-100B are associated with neurologic outcome after pediatric cardiac arrest. 29 Jun 2009
• Combination pharmacotherapy in the treatment of experimental cardiac arrest. 29 Jun 2009
• Influence of methylprednisolone on levels of neuron-specific enolase in cardiac surgery: a corticosteroid derivative to decrease possible neuronal damage. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Phosphopyruvate Hydratase'

Definition: A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity.

Chemical name: 2-Phospho-D-glycerate hydro-lyase

Registry Number: EC 4.2.1.11

Descriptor UI: D010751

Alternative terms: Phosphopyruvate Hydratase; Hydratase, Phosphopyruvate; 2-Phospho-D-Glycerate Hydrolase; 2 Phospho D Glycerate Hydrolase; Enolase; 2-Phospho-D-Glycerate Hydro-Lyase; 2 Phospho D Glycerate Hydro Lyase; Hydro-Lyase, 2-Phospho-D-Glycerate; 2-Phosphoglycerate Dehydratase; 2 Phosphoglycerate Dehydratase; Dehydratase, 2-Phosphoglycerate; beta-Enolase; beta Enolase; Muscle-Specific Enolase; Enolase, Muscle-Specific; Muscle Specific Enolase; Enolase 3; gamma-Enolase; gamma Enolase; Nervous System-Specific Enolase; Enolase, Nervous System-Specific; Nervous System Specific Enolase; System-Specific Enolase, Nervous; Neuron-Specific Enolase; Enolase, Neuron-Specific; Neuron Specific Enolase; Enolase 2; alpha-Enolase; alpha Enolase; Non-Neuronal Enolase; Enolase, Non-Neuronal; Non Neuronal Enolase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.520.241.300.500;

History Note: 73(64)