Pindolol
Research News and Information

Sunday, November 22, 2009

Cell-based beta2-adrenergic receptor-ligand binding assay using synthesized europium-labeled ligands and time-resolved fluorescence.

19 May 2009 High-sensitivity, high-throughput, and user-friendly lanthanide-based assays for receptor-ligand interactions provide an attractive alternative to the traditional radioligand displacement assays. In this study, three small-molecule pindolol ligand ... Read more...

Pindolol augmentation enhances response outcomes in first depressive episodes.

3 May 2009 Effectiveness of Pindolol addition to SSRIs is still a matter of debate. Recently, Geretsegger et al. [Geretsegger, C., Bitterlich, W., Stelzig, R., Stuppaeck, C., Bondy, B. and Aichhorn, W. (2008) Paroxetine with Pindolol augmentation: a ... Read more...

Placental and fetal hemodynamics after labetalol or pindolol in a sheep model of increased placental vascular resistance and maternal hypertension.

18 Apr 2009 We investigated the effects of labetalol and pindolol on uterine, placental, and fetal hemodynamics following norepinephrine-induced maternal hypertension in a sheep model of increased placental vascular resistance. Also, we examined fetal and ... Read more...

Latest indexed articles for 'Pindolol'

These are the very latest articles for this heading:

• Cell-based beta2-adrenergic receptor-ligand binding assay using synthesized europium-labeled ligands and time-resolved fluorescence. 19 May 2009
• Pindolol augmentation enhances response outcomes in first depressive episodes. 3 May 2009
• Placental and fetal hemodynamics after labetalol or pindolol in a sheep model of increased placental vascular resistance and maternal hypertension. 18 Apr 2009
• X-ray structure breakthroughs in the GPCR transmembrane region. 25 Feb 2009
• Heart rate variability in rats with experimental chronic heart failure and long-term exposure to beta-adrenoblockers. 30 Jan 2009
• WAY 100635 produces discriminative stimulus effects in rats mediated by dopamine D(4) receptor activation. 30 Jan 2009
• Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs. 30 Dec 2008
• Preparation and evaluation of propranolol molecularly imprinted solid-phase microextraction fiber for trace analysis of beta-blockers in urine and plasma samples. 28 Nov 2008
• Micelle to solvent stacking of organic cations in capillary zone electrophoresis with electrospray ionization mass spectrometry. 28 Nov 2008
• A study of the structure of the pindolol based on infrared spectroscopy and natural bond orbital theory. 26 Nov 2008
• Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats. 25 Nov 2008
• Beta blockers for peripheral arterial disease. 6 Oct 2008
• Preservation of the positive lusitropic effect of beta-adrenoceptors stimulation in diabetic cardiomyopathy. 29 Sep 2008
• Effects of alcohols on CE enantioseparation of basic drugs with native gamma-CD as chiral selector. 30 Jul 2008
• Simultaneous determination of beta-blockers in human plasma using liquid chromatography-tandem mass spectrometry. 29 Jun 2008
• Structure of a beta1-adrenergic G-protein-coupled receptor. 23 Jun 2008
• Evaluation of monolithic packed 96-tips and liquid chromatography-tandem mass spectrometry for extraction and quantification of pindolol and metoprolol in human plasma samples. 11 May 2008
• [5-HT1A/1B receptors, alpha2-adrenoceptors and the post-receptor adenylate cyclase activation in the mice brain are involved in the antidepressant-like action of agmatine] 29 Apr 2008
• Serotonin receptors contribute to the promnesic effects of P. olacoides (Marapuama). 29 Apr 2008
• Lithium overcomes the influence of 5-HTTLPR gene polymorphism on antidepressant response to sleep deprivation. 30 Mar 2008

See a longer list of these articles.

Technical information about 'Pindolol'

Definition: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)

Chemical name: 2-Propanol, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-

Registry Number: 13523-86-9

Descriptor UI: D010869

Alternative terms: Pindolol; Prindolol; Visken; LB-46; LB 46; LB46;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Adrenergic beta-Antagonists; Antihypertensive Agents; Serotonin Antagonists; Vasodilator Agents;

Tree Number: D02.033.100.624.748; D02.033.755.624.748; D02.092.063.624.698.699;

History Note: 73