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Piperazines - Pharmacology
Research News and Information
Saturday, November 21, 2009
6 Oct 2009 
Protease activated receptors (PARs) or thrombin receptors constitute a class of G-protein-coupled receptors (GPCRs) implicated in the activation of many physiological mechanisms. Thus, thrombin activates many cell types such as vascular smooth ... Read more...
29 Sep 2009 OBJECTIVE: The pharmacokinetic (PK) and pharmacodynamic (PD) responses to prasugrel were compared in three studies of healthy subjects vs. those with moderate or end-stage renal impairment. METHODS: Two of the three protocols were parallel-design, ... Read more...
Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease.
29 Sep 2009 BACKGROUND AND OBJECTIVE: Prasugrel is a thienopyridine antiplatelet agent under investigation for the prevention of atherothrombotic events in patients with acute coronary syndrome who undergo percutaneous coronary intervention. Patients with ... Read more...
Latest indexed articles for 'Piperazines - Pharmacology'
These are the very latest articles for this heading:
- Discovery of novel protease activated receptors 1 antagonists with potent antithrombotic activity in vivo. 6 Oct 2009
- Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease. 29 Sep 2009
- Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease. 29 Sep 2009
- Effectiveness of daily use of brimonidine as antimydriatic agent.
29 Sep 2009 - In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. 29 Sep 2009
- Prostate growth inhibition by subtype-selective alpha(1)-adrenoceptor antagonist naftopidil in benign prostatic hyperplasia. 29 Sep 2009
- Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. 25 Sep 2009
- Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3. 22 Sep 2009
- Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration. 22 Sep 2009
- Sildenafil increases endothelial progenitor cell function and improves ischemia-induced neovascularization in hypercholesterolemic apolipoprotein E-deficient mice. 19 Sep 2009
- Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemia-reperfusion. 16 Sep 2009
- MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine. 15 Sep 2009
- Selective expression of ligand-gated ion channels in L5 pyramidal cell axons. 14 Sep 2009
- Ranolazine as a cardioplegia additive improves recovery of diastolic function in isolated rat hearts. 13 Sep 2009
- Serotonin targets inhibitory synapses to induce modulation of network functions. 10 Sep 2009
- A multivalent approach to the design and discovery of orally efficacious 5-HT4 receptor agonists. 8 Sep 2009
- Cyclo(His-Pro) up-regulates heme oxygenase 1 via activation of Nrf2-ARE signalling. 5 Sep 2009
- Prasugrel (Effient) vs. clopidogrel (Plavix). 5 Sep 2009
- Approach sensitivity in the retina processed by a multifunctional neural circuit. 4 Sep 2009
- Recent breakthroughs in the understanding and management of chronic eosinophilic leukemia. 30 Aug 2009
See a longer list of these articles.
Technical information about 'Piperazines'
Registry Number: 0
Descriptor UI: D010879
Alternative terms: Piperazines;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D03.383.606;