Placebos
Research News and Information

Sunday, November 22, 2009

Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures.

30 Oct 2009 OBJECTIVES: To evaluate the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive therapy in adults with partial-onset seizures. MATERIAL AND METHODS: Double-blind, placebo-controlled, parallel-group, multicenter study consisting of an ... Read more...

A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies.

30 Oct 2009 CONTEXT: Little direct evidence exists on the relative efficacies of different smoking cessation pharmacotherapies, yet such evidence is needed to make informed decisions about their clinical use. OBJECTIVE: To assess the relative efficacies of 5 ... Read more...

Direct evidence for spinal cord involvement in placebo analgesia.

14 Oct 2009 Placebo analgesia is a prime example of the impact that psychological factors have on pain perception. We used functional magnetic resonance imaging of the human spinal cord to test the hypothesis that placebo analgesia results in a reduction of ... Read more...

Latest indexed articles for 'Placebos'

These are the very latest articles for this heading:

• Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. 30 Oct 2009
• A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies. 30 Oct 2009
• Missed opportunities in the trial on proton-pump inhibitor therapy in bleeding peptic ulcers. 18 Oct 2009
• Direct evidence for spinal cord involvement in placebo analgesia. 14 Oct 2009
• Placebo controls, exorcisms, and the devil. 8 Oct 2009
• Letter by Attaran regarding article, "Cardiac Ischemic Preconditioning in Coronary Stenting (CRISP Stent) study: a prospective, randomized control trial". 4 Oct 2009
• Effects of preoperative ibuprofen on pain after separator placement. 29 Sep 2009
• Randomized, controlled trial of telcagepant for the acute treatment of migraine. 20 Sep 2009
• Randomized double-blind placebo-controlled trial of thalidomide in combination with gemcitabine and Carboplatin in advanced non-small-cell lung cancer. 19 Sep 2009
• Effects of telmisartan, ramipril, and their combination on left ventricular hypertrophy in individuals at high vascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global End Point Trial and the Telmisartan Randomized Assessment Study in ACE Intolerant Subjects With Cardiovascular Disease. 19 Sep 2009
• Myocardial salvage through coronary collateral growth by granulocyte colony-stimulating factor in chronic coronary artery disease: a controlled randomized trial. 19 Sep 2009
• Randomized, double-blind, placebo-controlled evaluation of the efficacy of oral psoralen plus ultraviolet A for the treatment of plaque-type psoriasis using the Psoriasis Area Severity Index score (improvement of 75% or greater) at 12 weeks. 16 Sep 2009
• Analysis of stroke in ATHENA: a placebo-controlled, double-blind, parallel-arm trial to assess the efficacy of dronedarone 400 mg BID for the prevention of cardiovascular hospitalization or death from any cause in patients with atrial fibrillation/atrial flutter. 12 Sep 2009
• Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11). 6 Sep 2009
• Design, statistical analysis and sample size calculation of a phase IIb/III study of linagliptin versus voglibose and placebo. 3 Sep 2009
• Current Alzheimer's disease clinical trials: methods and placebo outcomes. 30 Aug 2009
• The cost of restricting knowledge. 30 Aug 2009
• Randomized controlled trial of interventions for young people at ultra-high risk of psychosis: study design and baseline characteristics. 30 Aug 2009
• Clinical messages from the Treatment for Adolescents With Depression Study (TADS). 30 Aug 2009
• Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Placebos'

Definition: Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.

Registry Number: 0

Descriptor UI: D010919

Alternative terms: Placebos; Sham Treatment;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications;

Tree Number: D26.660; E02.785;

Technical Notes: usually NIM; do not index routinely for articles on CLINICAL TRIALS; DOUBLE-BLIND METHOD; etc., unless particularly discussed; Manual 18.12.13