Plant Extracts - Pharmacokinetics
Research News and Information

Sunday, November 22, 2009

The pharmacokinetic behavior of the soy isoflavone metabolite S-(-)equol and its diastereoisomer R-(+)equol in healthy adults determined by using stable-isotope-labeled tracers.

24 Aug 2009 BACKGROUND: The nonsteroidal estrogen equol occurs as diastereoisomers, S-(-)equol and R-(+)equol, both of which have significant biological actions. S-(-)equol, the naturally occurring enantiomer produced by 20-30% of adults consuming soy foods, ... Read more...

Metabolites are key to understanding health effects of wine polyphenolics.

27 Jul 2009 Phenolic compounds in grapes and wine are grouped within the following major classes: stilbenes, phenolic acids, ellagitannins, flavan-3-ols, anthocyanins, flavonols, and proanthocyanidins. Consumption of foods containing phenolic substances has ... Read more...

[Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability]

18 Jul 2009 The Ginkgo biloba extract EGb 761 interferes with pathomechanisms relevant to dementia, such as Abeta aggregation, mitochondrial dysfunction, insulin resistance, and hypoperfusion. The efficacy of EGb 761 in the treatment of dementia (Alzheimer's ... Read more...

Latest indexed articles for 'Plant Extracts - Pharmacokinetics'

These are the very latest articles for this heading:

• Toxicity issues surrounding herbal use internationally and the U.S. Foreword. 29 Sep 2009
• The pharmacokinetic behavior of the soy isoflavone metabolite S-(-)equol and its diastereoisomer R-(+)equol in healthy adults determined by using stable-isotope-labeled tracers. 24 Aug 2009
• Metabolites are key to understanding health effects of wine polyphenolics. 27 Jul 2009
• [Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability] 18 Jul 2009
• High-performance liquid chromatography method for determination of carnosic acid in rat plasma and its application to pharmacokinetic study. 29 Jun 2009
• Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits. 29 Jun 2009
• Absorption of andrographolides from Andrographis paniculata and its effect on CCl(4)-induced oxidative stress in rats. 16 Jun 2009
• Caulis Sinomenii extracts activate DA/NE transporter and inhibit 5HT transporter. 31 May 2009
• Antiviral drug disposition and natural health products: risk of therapeutic alteration and resistance. 30 May 2009
• Characterization of metabolites in rat plasma after intravenous administration of salvianolic acid A by liquid chromatography/time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry. 30 May 2009
• Changes in the brain cortex of rabbits on a cholesterol-rich diet following supplementation with a herbal extract of Tribulus terrestris. 30 May 2009
• New perspectives for synergy research with the "omic"-technologies. 30 May 2009
• In vivo pharmacokinetics comparisons of icariin, emodin and psoralen from gan-kang granules and extracts of herba Epimedii, Nepal dock root, Ficus hirta yahl. 16 May 2009
• Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. 27 Apr 2009
• Simultaneous determination of magnolin and epimagnolin A in rat plasma by liquid chromatography with tandem mass spectrometry: Application to pharmacokinetic study of a purified extract of the dried flower buds of Magnolia fargesii, NDC-052 in rats. 5 Apr 2009
• [Study on vitro release and transdermal behaviors of Yulian cataplasm] 30 Mar 2009
• Potential interactions with herbal medications and midazolam. 30 Mar 2009
• MF-101, an estrogen receptor beta agonist for the treatment of vasomotor symptoms in peri- and postmenopausal women. 30 Mar 2009
• Exposure and toxicity of green tea polyphenols in fasted and non-fasted dogs. 22 Mar 2009
• Melanin-concentrating hormone-1 receptor antagonism and anti-obesity effects of ethanolic extract from Morus alba leaves in diet-induced obese mice. 16 Mar 2009

See a longer list of these articles.

Technical information about 'Plant Extracts'

Definition: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.

Registry Number: 0

Descriptor UI: D010936

Alternative terms: Plant Extracts; Extracts, Plant;

Related Mesh Headings: Phytotherapy;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D20.215.784.500; D26.667;

History Note: 76(67); was see under PLANTS 1975

Technical Notes: coordinate with specific plant and PLANT COMPONENTS term; for use in therapy coordinate IM or NIM with phytotherapy (IM) + disease/drug ther (IM) + specific chemical / ther use (IM) if pertinent; Manual 26.29; extracts of medicinal plants in Chinese medicine = PLANT EXTRACTS, CHINESE see DRUGS, CHINESE HERBAL