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Plasmids - Genetics
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Definition of 'Plasmids'

Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.

Common names: Plasmids; Plasmid; Episomes; Episome

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Sunday, November 22, 2009

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.

21 Sep 2009 The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence countermeasures, which include the production of type I interferon (IFN). However, little is known about how the innate ... Read more...


Protein and DNA effectors control the TraI conjugative helicase of plasmid R1.

16 Sep 2009 The mechanisms controlling progression of conjugative DNA processing from a preinitiation stage of specific plasmid strand cleavage at the transfer origin to a stage competent for unwinding the DNA strand destined for transfer remain obscure. Linear ... Read more...


Plasmid r1 conjugative DNA processing is regulated at the coupling protein interface.

16 Sep 2009 Selective substrate uptake controls initiation of macromolecular secretion by type IV secretion systems in gram-negative bacteria. Type IV coupling proteins (T4CPs) are essential, but the molecular mechanisms governing substrate entry to the ... Read more...

 

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Technical information about 'Plasmids'

Definition: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.

Descriptor UI: D010957

Alternative terms: Plasmids; Plasmid; Episomes; Episome;

Related Mesh Headings: Extrachromosomal Inheritance; Genetic Vectors;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: G05.360.600;

Online Note: use PLASMIDS to search EPISOMES 1975-77

History Note: 78(75); was see under EXTRACHROMOSOMAL INHERITANCE 1975-77; EPISOMES was see under EXTRACHROMOSOMAL INHERITANCE 1975-77

Technical Notes: GEN; prefer specifics

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