Platelet Aggregation - Physiology
Research News and Information

Sunday, November 22, 2009

Increased leukocyte-platelet interactions during circulatory support with left ventricular assist devices.

30 Aug 2009 The interaction of circulating monocytes and platelets may contribute to thrombosis and inflammation in heart failure. We studied platelet and monocyte activation in 15 patients with end-stage heart failure who underwent left ventricular assist ... Read more...

STIM1, Orai1 and hTRPC1 are important for thrombin- and ADP-induced aggregation in human platelets.

16 Aug 2009 Ca(2+) entry, particularly store-operated Ca(2+) entry (SOCE), has been reported to be crucial for a variety of cellular functions. SOCE is a mechanism regulated by the Ca(2+) content of the stores, where the intraluminal Ca(2+) sensor STromal ... Read more...

Platelet dense-granule secretion plays a critical role in thrombosis and subsequent vascular remodeling in atherosclerotic mice.

15 Aug 2009 BACKGROUND: Platelet aggregation plays a critical role in myocardial infarction and stroke; however, the role of platelet secretion in atherosclerotic vascular disease is poorly understood. Therefore, we examined the hypothesis that platelet ... Read more...

Latest indexed articles for 'Platelet Aggregation - Physiology'

These are the very latest articles for this heading:

• Assessment of platelet function in whole blood by multiple electrode aggregometry: transport of samples using a pneumatic tube system. 30 Oct 2009
• Increased leukocyte-platelet interactions during circulatory support with left ventricular assist devices. 30 Aug 2009
• Aspirin resistance. 30 Aug 2009
• STIM1, Orai1 and hTRPC1 are important for thrombin- and ADP-induced aggregation in human platelets. 16 Aug 2009
• Platelet dense-granule secretion plays a critical role in thrombosis and subsequent vascular remodeling in atherosclerotic mice. 15 Aug 2009
• Cancer cell-derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo. 8 Aug 2009
• Collagen-induced p38 MAP kinase activation is a biomarker of platelet hyper-aggregation in patients with diabetes mellitus. 19 Jul 2009
• Leukocyte-platelet aggregates in acute and subacute ischemic stroke. 14 Jul 2009
• Hostility and platelet reactivity in individuals without a history of cardiovascular disease events. 8 Jul 2009
• Genetic evidence for a predominant role of PI3Kbeta catalytic activity in ITAM- and integrin-mediated signaling in platelets. 8 Jun 2009
• Effect of pyridostigmine (Mestinon) on human platelet aggregation. 30 May 2009
• The physiology of wound healing: injury through maturation. 30 May 2009
• An assessment of cardiopulmonary bypass-induced changes in platelet function using whole blood and classical light transmission aggregometry: the results of a pilot study. 30 May 2009
• Platelet function and response to aspirin: gender-specific features and implications for female thrombotic risk and management. 16 May 2009
• Biological influence of physical exercise on hemostasis. 16 May 2009
• Whole blood multiple electrode aggregometry is a reliable point-of-care test of aspirin-induced platelet dysfunction. 11 May 2009
• Glycated albumin modulates platelet susceptibility to flow induced activation and aggregation. 29 Apr 2009
• Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD). 29 Apr 2009
• Regulation of plasmin-induced protease-activated receptor 4 activation in platelets. 29 Apr 2009
• Inhibition of platelet aggregation by 1-methyl-4-phenyl pyridinium ion (MPP+) through ATP depletion: Evidence for the reduced platelet activities in Parkinson's disease. 29 Apr 2009

See a longer list of these articles.

Technical information about 'Platelet Aggregation'

Definition: The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.

Descriptor UI: D010974

Alternative terms: Platelet Aggregation; Aggregation, Platelet;

Related Mesh Headings: Platelet Membrane Glycoproteins;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G09.188.124.552.624; G09.188.124.560.600.640;

Online Note: search PLATELET ADHESIVENESS 1974

History Note: 76(75); was see under PLATELET ADHESIVENESS 1974-75