Platelet Aggregation Inhibitors - Isolation & purification
Research News and Information

Monday, November 23, 2009

Inhibitory effects of oligopeptides from hen egg white on both human platelet aggregation and blood coagulation.

24 Jun 2009 Egg white proteins have many biological functions and substantial nutritional benefits when used as a food source; however, they also contain allergens such as ovalbumin, ovomucoid, and ovotransferrin. We prepared oligopeptides without allergens ... Read more...

Three new 7.3',8.5'-connected bicyclo[3.2.1]octanoids and other neolignans from leaves of Nectandra amazonum NEES. (Lauraceae).

30 May 2009 Three new 7.3',8.5'-connected (macrophyllin-type) bicyclo[3.2.1]octanoid neolignans (nectamazins A-C, 1-3) were isolated from leaves of Nectandra amazonum NEES., along with seven known neolignans (4-10). The structures of 1-3 were characterized by ... Read more...

NPP-BJ, a nucleotide pyrophosphatase/phosphodiesterase from Bothrops jararaca snake venom, inhibits platelet aggregation.

26 May 2009 Enzymes of the pyrophosphatase/phosphodiesterase family have multiple roles in extracellular nucleotide metabolism and in the regulation of nucleotide-based intercellular signaling. Snake venoms contain enzymes that hydrolyze nucleic acids and ... Read more...

Latest indexed articles for 'Platelet Aggregation Inhibitors - Isolation & purification'

These are the very latest articles for this heading:

• Inhibitory effects of oligopeptides from hen egg white on both human platelet aggregation and blood coagulation. 24 Jun 2009
• Three new 7.3',8.5'-connected bicyclo[3.2.1]octanoids and other neolignans from leaves of Nectandra amazonum NEES. (Lauraceae). 30 May 2009
• NPP-BJ, a nucleotide pyrophosphatase/phosphodiesterase from Bothrops jararaca snake venom, inhibits platelet aggregation. 26 May 2009
• VGD and MLD-motifs containing heterodimeric disintegrin viplebedin-2 from Vipera lebetina snake venom. Purification and cDNA cloning. 14 Mar 2009
• Triterpenes from Acanthopanax sessiliflorus fruits and their antiplatelet aggregation activities. 2 Mar 2009
• Purification and characterization of a new platelet aggregation inhibitor with dissociative effect on ADP-induced platelet aggregation, from the venom of Protobothrops elegans (Sakishima-habu). 26 Feb 2009
• Olive tree wood phenolic compounds with human platelet antiaggregant properties. 2 Feb 2009
• Validated column high-performance liquid chromatographic method for determination of aspirin and clopidogrel in combined tablets in the presence of degradation products formed under ICH-recommended stress conditions. 30 Dec 2008
• Separation and determination of clopidogrel and its impurities by capillary electrophoresis. 3 Nov 2008
• Inhibitory mechanisms of dihydroginsenoside Rg3 in platelet aggregation: critical roles of ERK2 and cAMP. 30 Oct 2008
• Anti-platelet effect of cumanastatin 1, a disintegrin isolated from venom of South American Crotalus rattlesnake. 30 Sep 2008
• Colombistatin: a disintegrin isolated from the venom of the South American snake (Bothrops colombiensis) that effectively inhibits platelet aggregation and SK-Mel-28 cell adhesion. 30 Sep 2008
• A new acidic myotoxic, anti-platelet and prostaglandin I2 inductor phospholipase A2 isolated from Bothrops moojeni snake venom. 25 Sep 2008
• [Expression, purification and characterization of a novel staphylokinase with anti-platelet aggregation activity] 2 Sep 2008
• Analysis of anti-platelet aggregation components of Rhizoma Zingiberis using chicken thrombocyte extract and high performance liquid chromatography. 3 Jul 2008
• Bioactive cembrane diterpenoids of Anisomeles indica. 10 Jun 2008
• Ethnopharmacological studies on antispasmodic and antiplatelet activities of Ficus carica. 9 Jun 2008
• Five new compounds from Dendrobium longicornu. 30 Mar 2008
• Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS. 30 Mar 2008
• Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor. 27 Mar 2008

See a longer list of these articles.

Technical information about 'Platelet Aggregation Inhibitors'

Definition: Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.

Registry Number: 0

Descriptor UI: D010975

Alternative terms: Platelet Aggregation Inhibitors; Aggregation Inhibitors, Platelet; Inhibitors, Platelet Aggregation; Blood Platelet Antiaggregants; Antiaggregants, Blood Platelet; Platelet Antiaggregants; Antiaggregants, Platelet; Blood Platelet Aggregation Inhibitors; Platelet Inhibitors; Inhibitors, Platelet; Antiplatelet Agents; Agents, Antiplatelet; Antiplatelet Drugs; Drugs, Antiplatelet; Platelet Antagonists; Antagonists, Platelet; Blood Platelet Antagonists; Antagonists, Blood Platelet;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.502.780;

History Note: 88

Technical Notes: DF: PLATELET INHIB