Platelet Aggregation
Research News and Information

Saturday, November 21, 2009

A randomized clinical trial investigating the relationship between aprotinin and hypercoagulability in off-pump coronary surgery.

30 Oct 2009 BACKGROUND: Off-pump coronary artery bypass (OPCAB) surgery is associated with a hypercoagulable state in which the platelet thrombin receptor, protease-activated receptor-1 (PAR-1), helps propagate a thrombin burst within saphenous vein grafts. ... Read more...

Predictive values of post-treatment adenosine diphosphate-induced aggregation and vasodilator-stimulated phosphoprotein index for stent thrombosis after acute coronary syndrome in clopidogrel-treated patients.

13 Oct 2009 A low response to clopidogrel has been associated with an increased risk of stent thrombosis. However, the definition of a nonresponse to clopidogrel remains controversial, and different tests have been used to assess the clopidogrel response. The ... Read more...

Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury.

3 Oct 2009 Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-associated mortality in the US. Previously, we established an immune-mediated TRALI mouse model, wherein mice with cognate antigen were challenged with MHC class I ... Read more...

Latest indexed articles for 'Platelet Aggregation'

These are the very latest articles for this heading:

• Assessment of platelet function in whole blood by multiple electrode aggregometry: transport of samples using a pneumatic tube system. 30 Oct 2009
• A randomized clinical trial investigating the relationship between aprotinin and hypercoagulability in off-pump coronary surgery. 30 Oct 2009
• Predictive values of post-treatment adenosine diphosphate-induced aggregation and vasodilator-stimulated phosphoprotein index for stent thrombosis after acute coronary syndrome in clopidogrel-treated patients. 13 Oct 2009
• Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. 3 Oct 2009
• Letter by de Miguel Castro et al regarding article, "cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up". 27 Sep 2009
• Increased leukocyte-platelet interactions during circulatory support with left ventricular assist devices. 30 Aug 2009
• Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: importance of the interactions between the D residue and integrin. 30 Aug 2009
• Possible involvement of chemokine-induced platelet activation in thrombophilic diathesis of antiphospholipid syndrome. 30 Aug 2009
• Relative contributions of collagen and tissue factor to thrombus formation on damaged vascular vessels: in-vitro studies with circulating blood. 30 Aug 2009
• Ultrastructural changes of platelet aggregates and fibrin networks in a patient with renal clear cell adenocarcinoma: a scanning electron microscopy study. 30 Aug 2009
• Aspirin resistance. 30 Aug 2009
• Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. 29 Aug 2009
• Characterization of a novel focal adhesion kinase inhibitor in human platelets. 26 Aug 2009
• [Cyclooxygenase inhibitors: adverse drug reactions are unavoidable, but only a few are (acutely) dangerous] 26 Aug 2009
• Tailoring antiplatelet therapy based on pharmacogenomics: how well do the data fit? 24 Aug 2009
• Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. 24 Aug 2009
• STIM1, Orai1 and hTRPC1 are important for thrombin- and ADP-induced aggregation in human platelets. 16 Aug 2009
• Platelet dense-granule secretion plays a critical role in thrombosis and subsequent vascular remodeling in atherosclerotic mice. 15 Aug 2009
• Platelet reactivity and stent thrombosis: still some issues to solve. 9 Aug 2009
• PAF-antagonistic bicyclo[3.2.1]octanoid neolignans from leaves of Ocotea macrophylla Kunth. (Lauraceae). 8 Aug 2009

See a longer list of these articles.

Technical information about 'Platelet Aggregation'

Definition: The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.

Descriptor UI: D010974

Alternative terms: Platelet Aggregation; Aggregation, Platelet;

Related Mesh Headings: Platelet Membrane Glycoproteins;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G09.188.124.552.624; G09.188.124.560.600.640;

Online Note: search PLATELET ADHESIVENESS 1974

History Note: 76(75); was see under PLATELET ADHESIVENESS 1974-75