Polyethylene Glycols - Pharmacology
Research News and Information

Sunday, November 22, 2009

Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up.

29 Sep 2009 Hepatitis C associated hypolipidemia has been demonstrated in studies from Europe and Africa. In two linked studies, we evaluated the relationship between hepatitis C infection and treatment with lipid levels in an American cohort and determined the ... Read more...

Impact of high-dose peginterferon alfa-2A on virological response rates in patients with hepatitis C genotype 1: a randomized controlled trial.

29 Sep 2009 This study tested the hypothesis that high-dose peginterferon alfa-2a (PEG-IFNalpha-2a) for the first 12 weeks would increase early and sustained virological response (SVR) rates in patients with chronic hepatitis C genotype 1. Eight hundred ... Read more...

Appraising the apoptotic mimicry model and the role of phospholipids for poxvirus entry.

21 Sep 2009 Entry of vaccinia virus (VACV) into cells occurs by fusion with the plasma membrane and via a low pH-dependent endosomal pathway, presumably involving unidentified cellular receptors. In addition to approximately 25 viral proteins, the membrane of ... Read more...

Latest indexed articles for 'Polyethylene Glycols - Pharmacology'

These are the very latest articles for this heading:

• Police find range of drugs after trawling bins used by Tour de France cyclists. 11 Oct 2009
• Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up. 29 Sep 2009
• Impact of high-dose peginterferon alfa-2A on virological response rates in patients with hepatitis C genotype 1: a randomized controlled trial. 29 Sep 2009
• Appraising the apoptotic mimicry model and the role of phospholipids for poxvirus entry. 21 Sep 2009
• [TNF-alpha blocking therapy in chronic inflammatory bowel disease] 18 Sep 2009
• Genomics: Hepatitis C virus gets personal. 15 Sep 2009
• A possible relationship between brain-derived adrenomedullin and oxytocin in the regulation of sodium balance. 30 Aug 2009
• Tumor necrosis factor alpha and RANKL blockade cannot halt bony spur formation in experimental inflammatory arthritis. 30 Aug 2009
• Single molecule measurements of F1-ATPase reveal an interdependence between the power stroke and the dwell duration. 23 Aug 2009
• Transcriptional and metabolic profiles of Lolium perenne L. genotypes in response to a PEG-induced water stress. 17 Aug 2009
• Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. 14 Aug 2009
• Antifibrotics for chronic hepatitis C. 30 Jul 2009
• Novel characteristics of sophorolipids, yeast glycolipid biosurfactants, as biodegradable low-foaming surfactants. 30 Jul 2009
• NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. 27 Jul 2009
• Endogenous interleukin-10 inhibits angiotensin II-induced vascular dysfunction. 18 Jul 2009
• Acid-sensitive outwardly rectifying anion channels in human erythrocytes. 30 Jun 2009
• [The role of changes in matrix metalloproteases and chitotriosidase in the mechanism of protective effect of atorvastatin in experimental murine lipemia] 29 Jun 2009
• [Changes in erythrocyte membrane-cytoskeleton complex, induced by dimethyl sulfoxide, polyethylene glycol, and low temperature] 29 Jun 2009
• Involvement of protein phosphorylation in water stress-induced antioxidant defense in maize leaves. 29 Jun 2009
• Effect of polyethyleneglycol spacer on the binding properties of nuclear localization signal-modified liposomes to isolated nucleus. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Polyethylene Glycols'

Definition: Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.

Registry Number: 0

Descriptor UI: D011092

Alternative terms: Polyethylene Glycols; Glycols, Polyethylene; Polyethylene Glycol; Glycol, Polyethylene; Polyethylene Oxide; Oxide, Polyethylene; Polyethyleneoxide; Polyoxyethylenes; Macrogols; Carbowax-400; Carbowax 400; Carbowax400; PEG 1000; 1000, PEG; PEG 8000; 8000, PEG; Polyethylene Glycol 2000; 2000, Polyethylene Glycol; Glycol 2000, Polyethylene; Tritons; Vigilon; Polyethylene Glycol 400; 400, Polyethylene Glycol; Glycol 400, Polyethylene; PEO-400; PEO 400; Peg 400; PEG-400; Polyethylene Glycol 4000; 4000, Polyethylene Glycol; Glycol 4000, Polyethylene; Polyethylene Glycol 6000; 6000, Polyethylene Glycol; Glycol 6000, Polyethylene; PEG 6000; 6000, PEG; Polyox FRA; FRA, Polyox; Carbowax 600; 600, Carbowax; Polyethylene Glycol 300; 300, Polyethylene Glycol; Glycol 300, Polyethylene; Macrogol 300; 300, Macrogol;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications;

Pharmacological Action: Surface-Active Agents; Drug Carriers; Solvents;

Tree Number: D02.033.455.250.700; D05.750.741; D25.720.741; J01.637.051.720.741;

Online Note: to search TRITONS use POLYETHYLENE GLYCOLS 1975-82 & SURFACE-ACTIVE AGENTS 1966-74

History Note: 74; TRITONS was heading 1975-82, was see under AMMONIUM COMPOUNDS 1975-78, was see under SURFACE-ACTIVE AGENTS 1963-74