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Polyethylene Glycols - Therapeutic use
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Definition of 'Polyethylene Glycols'

Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.

Common names: Polyethylene Glycols; Glycols, Polyethylene; Polyethylene Glycol; Glycol, Polyethylene; Polyethylene Oxide; Oxide, Polyethylene; Polyethyleneoxide; Polyoxyethylenes; Macrogols; Carbowax-400; Carbowax 400; Carbowax400; PEG 1000; 1000, PEG; PEG 8000; 8000, PEG; Polyethylene Glycol 2000

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Sunday, November 22, 2009

Efficacy and safety of pegylated interferon plus ribavirin in HIV and hepatitis C virus-coinfected patients with advanced immunosuppression.

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Peginterferon alpha-2a (40 kDa) and ribavirin: comparable rates of sustained virological response in sub-sets of older and younger HCV genotype 1 patients.

29 Sep 2009 The average age of patients initiating therapy for HCV is increasing, with older patients exhibiting lower responses to therapy than younger patients. Identification of those older patients likely to respond needs to be addressed. Using data from ... Read more...


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Technical information about 'Polyethylene Glycols'

Definition: Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.

Registry Number: 0

Descriptor UI: D011092

Alternative terms: Polyethylene Glycols; Glycols, Polyethylene; Polyethylene Glycol; Glycol, Polyethylene; Polyethylene Oxide; Oxide, Polyethylene; Polyethyleneoxide; Polyoxyethylenes; Macrogols; Carbowax-400; Carbowax 400; Carbowax400; PEG 1000; 1000, PEG; PEG 8000; 8000, PEG; Polyethylene Glycol 2000; 2000, Polyethylene Glycol; Glycol 2000, Polyethylene; Tritons; Vigilon; Polyethylene Glycol 400; 400, Polyethylene Glycol; Glycol 400, Polyethylene; PEO-400; PEO 400; Peg 400; PEG-400; Polyethylene Glycol 4000; 4000, Polyethylene Glycol; Glycol 4000, Polyethylene; Polyethylene Glycol 6000; 6000, Polyethylene Glycol; Glycol 6000, Polyethylene; PEG 6000; 6000, PEG; Polyox FRA; FRA, Polyox; Carbowax 600; 600, Carbowax; Polyethylene Glycol 300; 300, Polyethylene Glycol; Glycol 300, Polyethylene; Macrogol 300; 300, Macrogol;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications;

Pharmacological Action: Surface-Active Agents; Drug Carriers; Solvents;

Tree Number: D02.033.455.250.700; D05.750.741; D25.720.741; J01.637.051.720.741;

Online Note: to search TRITONS use POLYETHYLENE GLYCOLS 1975-82 & SURFACE-ACTIVE AGENTS 1966-74

History Note: 74; TRITONS was heading 1975-82, was see under AMMONIUM COMPOUNDS 1975-78, was see under SURFACE-ACTIVE AGENTS 1963-74

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