Polyethylene Glycols
Research News and Information

Sunday, November 22, 2009

Efficacy and safety of pegylated interferon plus ribavirin in HIV and hepatitis C virus-coinfected patients with advanced immunosuppression.

13 Oct 2009 BACKGROUND: The aim of this study was to assess the efficacy and safety of pegylated interferon (IFN) plus ribavirin (RBV) in human immunodeficiency virus (HIV) and hepatitis C virus (HCV)-coinfected patients with severe immunodeficiency in a ... Read more...

PEGylated nanoceria as radical scavenger with tunable redox chemistry.

12 Oct 2009 We report the direct synthesis of cerium oxide nanoparticles (CNPs) in polyethylene glycol (PEG) based solutions with efficient radical scavenging properties. Synthesis of CNPs in PEG demonstrated a concentration dependent (of PEG) redox activity ... Read more...

Enzyme-triggered disassembly of dendrimer-based amphiphilic nanocontainers.

12 Oct 2009 We demonstrate a new enzyme-induced disassembly of amphiphilic nanocontainers based on dendrimers. Disassembly and the ensuing release of noncovalently bound guest molecules are of great interest because of their implications in areas such as drug ... Read more...

Latest indexed articles for 'Polyethylene Glycols'

These are the very latest articles for this heading:

• Ribavirin plasma concentration predicts sustained virological response to peginterferon Alfa 2a plus ribavirin in previously treated HCV-HIV-coinfected patients. 30 Oct 2009
• Efficacy and safety of pegylated interferon plus ribavirin in HIV and hepatitis C virus-coinfected patients with advanced immunosuppression. 13 Oct 2009
• PEGylated nanoceria as radical scavenger with tunable redox chemistry. 12 Oct 2009
• Enzyme-triggered disassembly of dendrimer-based amphiphilic nanocontainers. 12 Oct 2009
• Police find range of drugs after trawling bins used by Tour de France cyclists. 11 Oct 2009
• Peginterferon alpha-2a (40 kDa) and ribavirin: comparable rates of sustained virological response in sub-sets of older and younger HCV genotype 1 patients. 29 Sep 2009
• Efficacy and safety of microfoam sclerotherapy in a patient with Klippel-Trenaunay syndrome and a patent foramen ovale. 29 Sep 2009
• Tissue-engineered polyethylene oxide/chitosan scaffolds as potential substitutes for articular cartilage. 29 Sep 2009
• PEGylation strategies for active targeting of PLA/PLGA nanoparticles. 29 Sep 2009
• Smooth muscle cell adhesion in surface-modified three-dimensional copolymer scaffolds prepared from co-continuous blends. 29 Sep 2009
• Are split bowel preparation regimens practical for morning colonoscopies? Implications of the new american college of gastroenterology colon cancer screening guidelines for real-world clinical practice. 29 Sep 2009
• Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up. 29 Sep 2009
• Hepatitis C drug development at a crossroads. 29 Sep 2009
• Impact of high-dose peginterferon alfa-2A on virological response rates in patients with hepatitis C genotype 1: a randomized controlled trial. 29 Sep 2009
• Fast fibrosis progression between repeated liver biopsies in patients coinfected with human immunodeficiency virus/hepatitis C virus. 29 Sep 2009
• Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers. 22 Sep 2009
• Appraising the apoptotic mimicry model and the role of phospholipids for poxvirus entry. 21 Sep 2009
• [TNF-alpha blocking therapy in chronic inflammatory bowel disease] 18 Sep 2009
• Genomics: Hepatitis C virus gets personal. 15 Sep 2009
• A novel synthetic route for the preparation of hydrolytically degradable synthetic hydrogels. 13 Sep 2009

See a longer list of these articles.

Technical information about 'Polyethylene Glycols'

Definition: Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.

Registry Number: 0

Descriptor UI: D011092

Alternative terms: Polyethylene Glycols; Glycols, Polyethylene; Polyethylene Glycol; Glycol, Polyethylene; Polyethylene Oxide; Oxide, Polyethylene; Polyethyleneoxide; Polyoxyethylenes; Macrogols; Carbowax-400; Carbowax 400; Carbowax400; PEG 1000; 1000, PEG; PEG 8000; 8000, PEG; Polyethylene Glycol 2000; 2000, Polyethylene Glycol; Glycol 2000, Polyethylene; Tritons; Vigilon; Polyethylene Glycol 400; 400, Polyethylene Glycol; Glycol 400, Polyethylene; PEO-400; PEO 400; Peg 400; PEG-400; Polyethylene Glycol 4000; 4000, Polyethylene Glycol; Glycol 4000, Polyethylene; Polyethylene Glycol 6000; 6000, Polyethylene Glycol; Glycol 6000, Polyethylene; PEG 6000; 6000, PEG; Polyox FRA; FRA, Polyox; Carbowax 600; 600, Carbowax; Polyethylene Glycol 300; 300, Polyethylene Glycol; Glycol 300, Polyethylene; Macrogol 300; 300, Macrogol;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; chemical synthesis; classification; diagnostic use; economics; history; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications;

Pharmacological Action: Surface-Active Agents; Drug Carriers; Solvents;

Tree Number: D02.033.455.250.700; D05.750.741; D25.720.741; J01.637.051.720.741;

Online Note: to search TRITONS use POLYETHYLENE GLYCOLS 1975-82 & SURFACE-ACTIVE AGENTS 1966-74

History Note: 74; TRITONS was heading 1975-82, was see under AMMONIUM COMPOUNDS 1975-78, was see under SURFACE-ACTIVE AGENTS 1963-74