Polymorphism, Genetic
Research News and Information

Saturday, November 21, 2009

IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.

29 Nov 2009 The mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes a protein that plays a critical role in tumor suppression, in part by modulating bioavailability of a potent mitogen, insulin-like growth factor-2 (IGF2). We tested ... Read more...

Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China.

29 Nov 2009 Isothiocyanates (ITC) in cruciferous vegetables may be chemopreventive against gastric cancer development. Glutathione S-transferases (GSTs) may modify the chemopreventive effect of ITC. The relationship between urinary total ITC and risk of gastric ... Read more...

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.

29 Nov 2009 P73 plays an important role in modulating cell-cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding p73 G4C14-to-A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). ... Read more...

Latest indexed articles for 'Polymorphism, Genetic'

These are the very latest articles for this heading:

• IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas. 29 Nov 2009
• Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China. 29 Nov 2009
• p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck. 29 Nov 2009
• Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection. 29 Nov 2009
• Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response. 29 Nov 2009
• The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. Nov 2009
• Common CCR 5 polymorphism in stroke: the CCR 5 delta32 polymorphism differentiates cardioembolism from other aetiologies of ischaemic cerebrovascular diseases. 30 Oct 2009
• MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer. 30 Oct 2009
• Effect of polymorphisms in the 3' untranslated region (3'-UTR) of vascular endothelial growth factor gene on gastric cancer and peptic ulcer diseases in Japan. 30 Oct 2009
• Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics-induced obsessive-compulsive symptoms. 30 Oct 2009
• Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. 30 Oct 2009
• Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia. 30 Oct 2009
• Polymorphisms in one-carbon metabolism pathway genes and risk for bladder cancer in a Tunisian population. 30 Oct 2009
• Genetic matters of CYP2D6 in breast cancer: copy number variations and nucleotide polymorphisms. 30 Oct 2009
• Anesthesia and pharmacogenomics: not ready for prime time. 30 Oct 2009
• Schizophrenia: the "BLOC" may be in the endosomes. 18 Oct 2009
• Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting. 13 Oct 2009
• Genetic susceptibility to rheumatoid arthritis: an emerging picture. 13 Oct 2009
• Impact of genetic polymorphisms in cytomegalovirus glycoprotein B on outcomes in solid-organ transplant recipients with cytomegalovirus disease. 13 Oct 2009
• Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. 13 Oct 2009

See a longer list of these articles.

Technical information about 'Polymorphism, Genetic'

Definition: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.

Descriptor UI: D011110

Alternative terms: Polymorphism, Genetic; Polymorphisms, Genetic; Genetic Polymorphism; Polymorphism (Genetics); Genetic Polymorphisms;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G05.365.795;

History Note: 2005(1968)

Technical Notes: DF: POLYMORPHISM