Polymorphism, Genetic
Research News and Information

Sunday, November 08, 2009

IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.

29 Nov 2009 The mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes a protein that plays a critical role in tumor suppression, in part by modulating bioavailability of a potent mitogen, insulin-like growth factor-2 (IGF2). We tested ... Read more...

Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China.

29 Nov 2009 Isothiocyanates (ITC) in cruciferous vegetables may be chemopreventive against gastric cancer development. Glutathione S-transferases (GSTs) may modify the chemopreventive effect of ITC. The relationship between urinary total ITC and risk of gastric ... Read more...

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.

29 Nov 2009 P73 plays an important role in modulating cell-cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding p73 G4C14-to-A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). ... Read more...

Latest indexed articles for 'Polymorphism, Genetic'

These are the very latest articles for this heading:

• IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas. 29 Nov 2009
• Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China. 29 Nov 2009
• p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck. 29 Nov 2009
• Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection. 29 Nov 2009
• Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response. 29 Nov 2009
• Anesthesia and pharmacogenomics: not ready for prime time. 30 Oct 2009
• Schizophrenia: the "BLOC" may be in the endosomes. 18 Oct 2009
• Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. 13 Oct 2009
• Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. 5 Oct 2009
• Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae. 30 Sep 2009
• Analysis of NQO1 polymorphisms and p53 protein expression in patients with hepatocellular carcinoma. 29 Sep 2009
• Association of functional gene polymorphism IL-1beta in patients with external apical root resorption. 29 Sep 2009
• Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population. 29 Sep 2009
• A common variation in EDAR is a genetic determinant of shovel-shaped incisors. 29 Sep 2009
• Interleukin-18 gene promoter polymorphism and the risk of nasopharyngeal carcinoma in a Chinese population. 29 Sep 2009
• No association between vitamin D receptor polymorphisms and coronary artery disease in a Chinese population. 29 Sep 2009
• Discussion: 'the interleukin-10 gene and cervical insufficiency' by Warren et al. 29 Sep 2009
• Molecular mapping of a stripe rust resistance gene in spring wheat cultivar Zak. 29 Sep 2009
• Hepatic drug transporters, old and new: pharmacogenomics, drug response, and clinical relevance. 29 Sep 2009
• Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Polymorphism, Genetic'

Definition: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.

Descriptor UI: D011110

Alternative terms: Polymorphism, Genetic; Polymorphisms, Genetic; Genetic Polymorphism; Polymorphism (Genetics); Genetic Polymorphisms;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G05.365.795;

History Note: 2005(1968)

Technical Notes: DF: POLYMORPHISM