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Polymorphism, Restriction Fragment Length
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Definition of 'Polymorphism, Restriction Fragment Length'

Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.

Common names: Polymorphism, Restriction Fragment Length; RFLPs; Restriction Fragment Length Polymorphisms; Restriction Fragment Length Polymorphism; RFLP

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Saturday, November 21, 2009

Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolates.

13 Nov 2009 Better understanding of the epidemiology and transmission patterns of human Pneumocystis should lead to improved strategies for preventing Pneumocystis pneumonia (PCP). We have developed a typing method for Pneumocystis jirovecii that is based on ... Read more...


Molecular epidemiology of Clostridium difficile over the course of 10 years in a tertiary care hospital.

13 Oct 2009 BACKGROUND: The molecular epidemiology of endemic and outbreak Clostridium difficile strains across time is not well known. METHODS: HindIII restriction endonuclease analysis (REA) typing was performed on available clinical C. difficile isolates ... Read more...


Molecular epidemiology of Mycobacterium tuberculosis in a South African community with high HIV prevalence.

13 Oct 2009 To explore the relationship between human immunodeficiency virus (HIV) and Mycobacterium tuberculosis genotypes, we performed IS6110-based restriction fragment-length polymorphism analysis on M. tuberculosis culture specimens from patients with ... Read more...

 

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Technical information about 'Polymorphism, Restriction Fragment Length'

Definition: Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.

Descriptor UI: D012150

Alternative terms: Polymorphism, Restriction Fragment Length; RFLPs; Restriction Fragment Length Polymorphisms; Restriction Fragment Length Polymorphism; RFLP;

Related Mesh Headings: Mutation; DNA Fingerprinting; Amplified Fragment Length Polymorphism Analysis;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G05.365.795.595;

Online Note: use POLYMORPHISM, RESTRICTION FRAGMENT LENGTH to search for RESTRICTION FRAGMENT LENGTH POLYMORPHISMS 1987-94

History Note: 95; was RESTRICTION FRAGMENT LENGTH POLYMORPHISMS 1987-94 (see under POLYMORPHISM (GENETICS) 1987-89)

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