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Polyneuropathies - Physiopathology
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Definition of 'Polyneuropathies'

Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.

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Sunday, November 22, 2009

Is there a need for long-term follow-up in chronic idiopathic polyneuropathy?

8 Sep 2009 OBJECTIVE: To evaluate the long-term functional status and well-being in patients with chronic idiopathic polyneuropathy (CIP) in comparison to Guillain-Barré syndrome (GBS) and healthy controls. MATERIALS AND METHODS: Forty-two CIP and 42 ... Read more...


Detection of anti-MAG antibodies in polyneuropathy associated with IgM monoclonal gammopathy.

30 Aug 2009 BACKGROUND: Detection of serum antibodies to myelin-associated glycoprotein (MAG) by Western blot (WB) is a valuable assay to diagnose a distinct type of demyelinating polyneuropathy with immunoglobulin M (IgM) monoclonal gammopathy. In this study, ... Read more...


Clinical characterization and successful treatment of 6 patients with Churg-Strauss syndrome-associated neuropathy.

Aug 2009 OBJECTIVE: To confirm the reported findings and clarify unknown clinical features of Churg-Strauss syndrome (CSS)-associated neuropathy and design appropriate treatment. PATIENTS AND METHODS: We assessed the clinical features of 6 patients with ... Read more...

 

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Technical information about 'Polyneuropathies'

Definition: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.

Descriptor UI: D011115

Alternative terms: Polyneuropathies; Polyneuropathy; Polyneuropathy, Motor; Motor Polyneuropathies; Motor Polyneuropathy; Polyneuropathies, Motor; Polyneuropathy, Familial; Familial Polyneuropathies; Familial Polyneuropathy; Polyneuropathies, Familial; Polyneuropathy, Inherited; Inherited Polyneuropathies; Inherited Polyneuropathy; Polyneuropathies, Inherited; Polyneuropathy, Acquired; Acquired Polyneuropathies; Acquired Polyneuropathy; Polyneuropathies, Acquired; Polyneuropathy, Critical Illness; Critical Illness Polyneuropathies; Critical Illness Polyneuropathy; Polyneuropathies, Critical Illness;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.668.829.800;

History Note: 2000(1966)

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