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Polyneuropathies
Research News and Information
Definition of 'Polyneuropathies'Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance. |
Monday, November 23, 2009
Vincristine: Can its therapeutic index be enhanced?
13 Dec 2009 
Vincristine is one of the most widely used and more effective drugs in paediatric oncology. The dose-limiting toxicity of neuropathy, lack of proven neuroprotective measures and an incomplete understanding of the pharmacokinetics and ... Read more...
[56-year-old patient with leg paresis, pulmonary infiltrates, and eosinophilia--Case 08/2009]
19 Oct 2009 HISTORY AND ADMISSION FINDINGS: A 56-year-old woman presented with progressive dyspnea and polyneuropathia. Medical history revealed a bronchial asthma and hypertension. She was in a reduced general condition and had to be admitted to the intensive ... Read more...
Is there a need for long-term follow-up in chronic idiopathic polyneuropathy?
8 Sep 2009 OBJECTIVE: To evaluate the long-term functional status and well-being in patients with chronic idiopathic polyneuropathy (CIP) in comparison to Guillain-Barré syndrome (GBS) and healthy controls. MATERIALS AND METHODS: Forty-two CIP and 42 ... Read more...
Latest indexed articles for 'Polyneuropathies'
These are the very latest articles for this heading:
- Vincristine: Can its therapeutic index be enhanced? 13 Dec 2009
- [56-year-old patient with leg paresis, pulmonary infiltrates, and eosinophilia--Case 08/2009] 19 Oct 2009
- Neurologic improvement after peripheral blood stem cell transplantation in poems.
4 Oct 2009 - Is there a need for long-term follow-up in chronic idiopathic polyneuropathy? 8 Sep 2009
- SLC25A19 mutation as a cause of neuropathy and bilateral striatal necrosis. 30 Aug 2009
- Cyclosporin treatment in three children with chronic inflammatory demyelinating neuropathy. 30 Aug 2009
- Detection of anti-MAG antibodies in polyneuropathy associated with IgM monoclonal gammopathy. 30 Aug 2009
- Quantitative sensation and autonomic test abnormalities in transthyretin amyloidosis polyneuropathy. 30 Aug 2009
- How should we deal with muscle weakness in critically ill patients? 30 Aug 2009
- Neuroendocrine impairments in inflammatory demyelinating polyneuropathies. 30 Aug 2009
- The roles of ethnicity and antiretrovirals in HIV-associated polyneuropathy: a pilot study. 13 Aug 2009
- Clinical characterization and successful treatment of 6 patients with Churg-Strauss syndrome-associated neuropathy. Aug 2009
- Fingolimod and related compounds in a spontaneous autoimmune polyneuropathy. Aug 2009
- [Polyneuropathies in vitamin B1 deficiency in Reunion and Mayotte islands in 70 patients of Maori and Comorian descent] 30 Jul 2009
- Avermectin intoxication with coma, myoclonus, and polyneuropathy. 30 Jul 2009
- Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of cisplatin-induced neuropathy.
13 Jul 2009 - [A case of neurofibromatosis type 2 (NF2) presenting with late-onset axonal polyneuropathy] 29 Jun 2009
- Critical illness polyneuropathy after Bacillus cereus sepsis in acute lymphoblastic leukemia. 29 Jun 2009
- Heart-lung transplantation in patients with pulmonary atresia and ventricular septal defect. 21 Jun 2009
- Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy. 13 Jun 2009
See a longer list of these articles.
Technical information about 'Polyneuropathies'
Definition: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
Descriptor UI: D011115
Alternative terms: Polyneuropathies; Polyneuropathy; Polyneuropathy, Motor; Motor Polyneuropathies; Motor Polyneuropathy; Polyneuropathies, Motor; Polyneuropathy, Familial; Familial Polyneuropathies; Familial Polyneuropathy; Polyneuropathies, Familial; Polyneuropathy, Inherited; Inherited Polyneuropathies; Inherited Polyneuropathy; Polyneuropathies, Inherited; Polyneuropathy, Acquired; Acquired Polyneuropathies; Acquired Polyneuropathy; Polyneuropathies, Acquired; Polyneuropathy, Critical Illness; Critical Illness Polyneuropathies; Critical Illness Polyneuropathy; Polyneuropathies, Critical Illness;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.668.829.800;
History Note: 2000(1966)