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Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
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Definition of 'Polyradiculoneuropathy, Chronic Inflammatory Demyelinating'

A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)

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Monday, November 23, 2009

Evidence-based treatment of chronic immune-mediated neuropathies.

30 Jul 2009 Immune-mediated neuropathies are treatable disorders that can result in considerable disability in some cases. Chronic immune-mediated neuropathies include chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy and ... Read more...


CD73 is expressed on invading T lymphocytes in the inflamed peripheral nerve.

30 Jul 2009 CD73 is a cell surface enzyme that modulates immune and inflammatory responses by affecting adenosine-receptor-mediated signaling. We examined its expression and cellular distribution in the inflamed human peripheral nerve. CD4+ and CD8+ T ... Read more...


Chronic inflammatory demyelinating polyneuropathy accompanied by chronic myelomonocytic leukemia: possible pathogenesis of autoimmunity in myelodysplastic syndrome.

7 Jul 2009 Paraneoplastic neuropathies have rarely been reported in patients with hematological malignancies. We report herein the case of a 65-year-old Japanese woman with chronic myelomonocytic leukemia (CMML) accompanying chronic inflammatory demyelinating ... Read more...

 

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Technical information about 'Polyradiculoneuropathy, Chronic Inflammatory Demyelinating'

Definition: A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)

Descriptor UI: D020277

Alternative terms: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Polyradiculoneuropathy, Chronic Inflammatory; Chronic Inflammatory Polyradiculoneuropathy; Chronic Inflammatory Polyradiculoneuropathies; Polyradiculoneuropathies, Chronic Inflammatory; Inflammatory Polyradiculopathy, Chronic; Chronic Inflammatory Polyradiculopathies; Chronic Inflammatory Polyradiculopathy; Inflammatory Polyradiculopathies, Chronic; Polyradiculopathies, Chronic Inflammatory; Polyradiculopathy, Chronic Inflammatory; CIDP; Chronic Inflammatory Demyelinating Polyradiculoneuropathy;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.114.750.175; C10.314.750.700; C10.668.829.800.750.600; C20.111.258.750.800;

History Note: 2000

Technical Notes: do not confuse X ref CHRONIC INFLAMMATORY POLYRADICULONEUROPATHY with POLYRADICULONEUROPATHY, ACUTE INFLAMMATORY see GUILLAIN-BARRE SYNDROME

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