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Polysaccharides
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Sunday, November 08, 2009

Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I.

18 Oct 2009 Sialylated forms of the Fc fragment of immunoglobulin G, produced by the human alpha2-6 sialyltransferase ST6Gal-I, were identified as potent anti-inflammatory mediators in a mouse model of rheumatoid arthritis and are potentially the active ... Read more...


Automated assay for fondaparinux (Arixtra) on the Dade Behring BCS XP.

29 Sep 2009 An assay for fondaparinux (Arixtra) is described based on a modified commercial assay for heparin. The assay is automated on a Dade Behring BCS XP (Siemens Healthcare Diagnostics, Deerfield, IL) and uses the inhibition of activated factor X to ... Read more...


Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides.

27 Sep 2009 Group B Streptococcus (GBS) causes serious infection in neonates and is an important target of vaccine development. Zwitterionic polysaccharides (ZPS), obtained through chemical introduction of positive charges into anionic polysaccharides (PS) from ... Read more...

 

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Technical information about 'Polysaccharides'

Registry Number: 0

Descriptor UI: D011134

Alternative terms: Polysaccharides; Glycans;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; ultrastructure;

Tree Number: D09.698;

Technical Notes: 13 or more units; GEN; prefer specifics

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