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Prefrontal Cortex - Injuries
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Definition of 'Prefrontal Cortex'

The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the mediodorsal nucleus of the thalamus. The prefrontal cortex receives afferent fibers from numerous structures of the diencephalon, mesencephalon, and limbic system as well as cortical afferents of visual, auditory, and somatic origin.

Common names: Prefrontal Cortex; Cortex, Prefrontal

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Sunday, November 22, 2009

Diffusion-tensor imaging implicates prefrontal axonal injury in executive function impairment following very mild traumatic brain injury.

28 Jun 2009 PURPOSE: To determine whether frontal white matter diffusion abnormalities can help predict acute executive function impairment after mild traumatic brain injury (mTBI). MATERIALS AND METHODS: This study had institutional review board approval, ... Read more...


Evidence of action sequence chunking in goal-directed instrumental conditioning and its dependence on the dorsomedial prefrontal cortex.

22 Jun 2009 The current study investigated the contribution of the dorsomedial prefrontal cortex (dmPFC) to instrumental action selection. We found that cell body lesions of the dmPFC, centered on the medial agranular area, spared rats' ability to choose ... Read more...


A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response.

Jun 2009 Complementing its roles in cognitive and affective information processing, the medial prefrontal cortex (mPFC) is a nodal point of a limbic forebrain circuit that modulates stress-related homeostatic mechanisms, including the ... Read more...

 

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Technical information about 'Prefrontal Cortex'

Definition: The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the mediodorsal nucleus of the thalamus. The prefrontal cortex receives afferent fibers from numerous structures of the diencephalon, mesencephalon, and limbic system as well as cortical afferents of visual, auditory, and somatic origin.

Descriptor UI: D017397

Alternative terms: Prefrontal Cortex; Cortex, Prefrontal;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.730.885.287.500.270.700;

History Note: 93

Technical Notes: "rostral part of the frontal lobe"

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