Presynaptic Terminals - Metabolism
Research News and Information

Tuesday, November 24, 2009

Extrasynaptic GABAA receptors: form, pharmacology, and function.

12 Oct 2009 GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABA(A) and GABA(B) receptors. Recently, a novel form of GABA(A) receptor-mediated inhibition, termed "tonic" inhibition, has been described. Whereas synaptic GABA(A) ... Read more...

Rapid assembly of functional presynaptic boutons triggered by adhesive contacts.

5 Oct 2009 CNS synapse assembly typically follows after stable contacts between "appropriate" axonal and dendritic membranes are made. We show that presynaptic boutons selectively form de novo following neuronal fiber adhesion to beads coated with ... Read more...

Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells.

29 Sep 2009 Local synapses formed by nondopamine cells within the ventral tegmental area (VTA) are thought to provide an important regulatory influence on the activity patterns of dopamine (DA) neurons. However, ultrastructural confirmation of intra-areal ... Read more...

Latest indexed articles for 'Presynaptic Terminals - Metabolism'

These are the very latest articles for this heading:

• Extrasynaptic GABAA receptors: form, pharmacology, and function. 12 Oct 2009
• Rapid assembly of functional presynaptic boutons triggered by adhesive contacts. 5 Oct 2009
• Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. 29 Sep 2009
• Time-dependent exposure of nicotine and smoke modulate ultrasubcellular organelle localization of dopamine D1 and D2 receptors in the rat caudate-putamen. 29 Sep 2009
• High-affinity kainate receptor subunits are necessary for ionotropic but not metabotropic signaling. 22 Sep 2009
• Sequential onset of presynaptic molecules during olfactory sensory neuron maturation. 18 Sep 2009
• PP2A and GSK-3beta act antagonistically to regulate active zone development. 14 Sep 2009
• Cholesterol, regulated exocytosis and the physiological fusion machine. 12 Sep 2009
• Rapid endocytosis does not recycle vesicles within the readily releasable pool. 31 Aug 2009
• Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. 31 Aug 2009
• Splice-specific roles of glycine receptor alpha3 in the hippocampus. 30 Aug 2009
• Facilitation of glutamate release from rat cerebral cortex nerve terminal by subanesthetic concentration propofol. 30 Aug 2009
• Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals. 30 Aug 2009
• Dopamine release at individual presynaptic terminals visualized with FFNs. 29 Aug 2009
• Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36. 28 Aug 2009
• Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor. 25 Aug 2009
• Location matters: synaptotagmin helps place vesicles near calcium channels. 25 Aug 2009
• Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. 23 Aug 2009
• Selective remodeling: refining neural connectivity at the neuromuscular junction. 23 Aug 2009
• Synaptic organization of the tectorecipient zone of the rat lateral posterior nucleus. 18 Aug 2009

See a longer list of these articles.

Technical information about 'Presynaptic Terminals'

Definition: The distal terminations of axons which are specialized for the release of neurotransmitters. Also included are varicosities along the course of axons which have similar specializations and also release transmitters. Presynaptic terminals in both the central and peripheral nervous systems are included.

Descriptor UI: D017729

Alternative terms: Presynaptic Terminals; Presynaptic Terminal; Terminal, Presynaptic; Terminals, Presynaptic; Nerve Endings, Presynaptic; Ending, Presynaptic Nerve; Endings, Presynaptic Nerve; Nerve Ending, Presynaptic; Presynaptic Nerve Ending; Presynaptic Nerve Endings; Synaptic Terminals; Synaptic Terminal; Terminal, Synaptic; Terminals, Synaptic; Axon Terminals; Axon Terminal; Terminal, Axon; Terminals, Axon; Synaptic Boutons; Bouton, Synaptic; Boutons, Synaptic; Synaptic Bouton;

Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.663.542.145.750; A08.850.700; A11.284.149.165.420.780.700; A11.671.137.750;

History Note: 94

Technical Notes: distal terminations of axons: note X ref; A 11 qualif except /cytol