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Procollagen - Genetics
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Definition of 'Procollagen'

A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-terminal and carboxyl-terminal ends of the polypeptide chains.

Common names: Procollagen; Procollagen Type M; Protocollagen

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Monday, November 23, 2009

Effect of exogenous hepatocyte growth factor on vocal fold fibroblasts.

30 Jul 2009 OBJECTIVES: We have previously demonstrated the therapeutic potential of hepatocyte growth factor (HGF) in the treatment of vocal fold scarring, although how exogenous HGF affects gene expression of endogenous HGF or extracellular matrix components ... Read more...


Regenerative effects of basic fibroblast growth factor on extracellular matrix production in aged rat vocal folds.

30 Jul 2009 OBJECTIVES: We investigated acute changes in extracellular matrix (ECM) gene expression and histologic changes in the deposition of collagen and hyaluronan (hyaluronic acid; HA) after basic fibroblast growth factor (bFGF) treatment of the aged rat ... Read more...


Fibronectin binds and enhances the activity of bone morphogenetic protein 1.

16 Jul 2009 Bone morphogenetic protein-1-like proteinases play key roles in formation of the extracellular matrix (ECM) in vertebrates via biosynthetic processing of precursors into mature functional proteins involved in ECM assembly. Such processing includes ... Read more...

 

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Technical information about 'Procollagen'

Definition: A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-terminal and carboxyl-terminal ends of the polypeptide chains.

Registry Number: 0

Descriptor UI: D011347

Alternative terms: Procollagen; Procollagen Type M; Protocollagen;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.811.690; D12.776.860.300.250.600;

History Note: 77

Technical Notes: coord IM with specific collagen (IM) if pertinent

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