Promoter Regions, Genetic - Genetics
Research News and Information

Sunday, November 22, 2009

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.

29 Nov 2009 The goal of the investigation was to test the hypothesis that the phosphoinositide-3 kinase (PI3K)/AKT signaling pathway regulates the expression of the major extracellular matrix component of the intervertebral disc, aggrecan, in nucleus pulposus ... Read more...

Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1.

29 Nov 2009 p21-Activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of Pak1 in gastric cancer remains unclear. In this study, we detected Pak1 ... Read more...

Latest indexed articles for 'Promoter Regions, Genetic - Genetics'

These are the very latest articles for this heading:

• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. 29 Nov 2009
• Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. 29 Nov 2009
• Deficient serum mannose-binding lectin levels and MBL2 polymorphisms increase the risk of single and recurrent Cryptosporidium infections in young children. 13 Nov 2009
• The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms. 13 Nov 2009
• Cytokines and signaling pathways regulating matrix metalloproteinase-9 (MMP-9) expression in corneal epithelial cells. 30 Oct 2009
• The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction. 21 Oct 2009
• Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production. 16 Oct 2009
• Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition. 13 Oct 2009
• The association between -1304T>G polymorphism in the promoter of MKK4 gene and the risk of sporadic colorectal cancer in southern Chinese population. 13 Oct 2009
• Drug-regulatable cancer cell death induced by BID under control of the tissue-specific, lung cancer-targeted TTS promoter system. 13 Oct 2009
• TGFbetaR2 aberrant methylation is a potential prognostic marker and therapeutic target in multiple myeloma. 13 Oct 2009
• Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats. 12 Oct 2009
• Gal4 turnover and transcription activation. 6 Oct 2009
• Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis. 29 Sep 2009
• Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors. 29 Sep 2009
• Oxidative DNA modifications in hypoxic signaling. 29 Sep 2009
• Discussion: 'the interleukin-10 gene and cervical insufficiency' by Warren et al. 29 Sep 2009
• Regulation of CDX2 expression in esophageal adenocarcinoma. 29 Sep 2009
• Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Promoter Regions, Genetic'

Definition: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.

Descriptor UI: D011401

Alternative terms: Promoter Regions, Genetic; Genetic Promoter Region; Genetic Promoter Regions; Promoter Region, Genetic; Region, Genetic Promoter; Regions, Genetic Promoter; Promoter Regions; Promoter Region; Region, Promoter; Regions, Promoter; Promotor Regions; Promotor Region; Region, Promotor; Regions, Promotor; Late Promoters, Genetic; Genetic Late Promoter; Late Promoter, Genetic; Middle Promoters, Genetic; Genetic Middle Promoters; Middle Promoter, Genetic; Promoters, Genetic Middle; rRNA Promoter; Promoter, rRNA; Promoters, rRNA; rRNA Promoters; Promoter, Genetic; Genetic Promoter; Genetic Promoters; Promoters, Genetic; Promotor, Genetic; Genetic Promotor; Genetic Promotors; Promotors, Genetic; Pseudopromoter, Genetic; Genetic Pseudopromoter; Genetic Pseudopromoters; Pseudopromoters, Genetic; Early Promoters, Genetic; Early Promoter, Genetic; Promoter, Genetic Early;

Related Mesh Headings: Genes, Reporter;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.570.080.689.675; G05.360.080.689.675; G05.360.340.024.340.137.750.680;

History Note: 2009 (1985); for PROMOTER, GENETIC use OPERON 1980-1984; for rRNA PROMOTER use rRNA OPERON 1990-1998