Promoter Regions, Genetic - Physiology
Research News and Information

Sunday, November 22, 2009

E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases.

15 Sep 2009 E2F1 is a key positive regulator of human cell proliferation and its activity is altered in essentially all human cancers. Deregulation of E2F1 leads to oncogenic DNA damage and anti-oncogenic apoptosis. The molecular mechanisms by which E2F1 ... Read more...

C/EBPbeta regulates metastatic gene expression and confers TNF-alpha resistance to prostate cancer cells.

13 Sep 2009 BACKGROUND: CCAAT/enhancer-binding protein beta (C/EBPbeta) is a transcription factor and consists of three isoforms, transcription-activating A/B (C/EBPbeta-AB) and transcription inhibitory C (C/EBPbeta-C). We previously reported that C/EBPbeta-C ... Read more...

Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway.

12 Sep 2009 BACKGROUND: Although inducible nitric oxide synthase (iNOS) is known to impart powerful protection against myocardial infarction, the mechanism for this salubrious action remains unclear. METHODS AND RESULTS: Adenovirus-mediated iNOS gene transfer ... Read more...

Latest indexed articles for 'Promoter Regions, Genetic - Physiology'

These are the very latest articles for this heading:

• E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases. 15 Sep 2009
• C/EBPbeta regulates metastatic gene expression and confers TNF-alpha resistance to prostate cancer cells. 13 Sep 2009
• Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway. 12 Sep 2009
• Regulation of vascular contractility and blood pressure by the E2F2 transcription factor. 12 Sep 2009
• An interactive regulatory network controls stress response in Bifidobacterium breve UCC2003. 2 Sep 2009
• Transcriptional regulation of the myosin heavy chain IIb gene in inactive rat soleus. 30 Aug 2009
• Divergent transcription: a new feature of active promoters. 17 Aug 2009
• Control of chicken CR1 retrotransposons is independent of Dicer-mediated RNA interference pathway. 17 Aug 2009
• Histone hyperacetylation within the beta-globin locus is context-dependent and precedes high-level gene expression. 16 Aug 2009
• Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells. 15 Aug 2009
• Cell cycle regulatory effects of retinoic Acid and forskolin are mediated by the cyclin C gene. 12 Aug 2009
• MACC1 controls Met: what a difference an Sp1 site makes. 11 Aug 2009
• Coupled RNA processing and transcription of intergenic primary microRNAs. 8 Aug 2009
• Identification and functional analyses of molecular haplotypes of the human osteoprotegerin gene promoter. 4 Aug 2009
• Gene activation by dissociation of an inhibitor from a transcriptional activation domain. Aug 2009
• DNA demethylation of the perforin promoter in CD4(+) T cells from patients with subacute cutaneous lupus erythematosus. Aug 2009
• TBP2 is a substitute for TBP in Xenopus oocyte transcription. Aug 2009
• Chromatin: sub out the replacement. 26 Jul 2009
• Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation. 24 Jul 2009
• Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells. 21 Jul 2009

See a longer list of these articles.

Technical information about 'Promoter Regions, Genetic'

Definition: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.

Descriptor UI: D011401

Alternative terms: Promoter Regions, Genetic; Genetic Promoter Region; Genetic Promoter Regions; Promoter Region, Genetic; Region, Genetic Promoter; Regions, Genetic Promoter; Promoter Regions; Promoter Region; Region, Promoter; Regions, Promoter; Promotor Regions; Promotor Region; Region, Promotor; Regions, Promotor; Late Promoters, Genetic; Genetic Late Promoter; Late Promoter, Genetic; Middle Promoters, Genetic; Genetic Middle Promoters; Middle Promoter, Genetic; Promoters, Genetic Middle; rRNA Promoter; Promoter, rRNA; Promoters, rRNA; rRNA Promoters; Promoter, Genetic; Genetic Promoter; Genetic Promoters; Promoters, Genetic; Promotor, Genetic; Genetic Promotor; Genetic Promotors; Promotors, Genetic; Pseudopromoter, Genetic; Genetic Pseudopromoter; Genetic Pseudopromoters; Pseudopromoters, Genetic; Early Promoters, Genetic; Early Promoter, Genetic; Promoter, Genetic Early;

Related Mesh Headings: Genes, Reporter;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.570.080.689.675; G05.360.080.689.675; G05.360.340.024.340.137.750.680;

History Note: 2009 (1985); for PROMOTER, GENETIC use OPERON 1980-1984; for rRNA PROMOTER use rRNA OPERON 1990-1998