Promoter Regions, Genetic
Research News and Information

Saturday, November 21, 2009

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.

29 Nov 2009 The goal of the investigation was to test the hypothesis that the phosphoinositide-3 kinase (PI3K)/AKT signaling pathway regulates the expression of the major extracellular matrix component of the intervertebral disc, aggrecan, in nucleus pulposus ... Read more...

Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1.

29 Nov 2009 p21-Activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of Pak1 in gastric cancer remains unclear. In this study, we detected Pak1 ... Read more...

Latest indexed articles for 'Promoter Regions, Genetic'

These are the very latest articles for this heading:

• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. 29 Nov 2009
• Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. 29 Nov 2009
• Epigenetic regulation of microRNA expression in colorectal cancer. 29 Nov 2009
• Deficient serum mannose-binding lectin levels and MBL2 polymorphisms increase the risk of single and recurrent Cryptosporidium infections in young children. 13 Nov 2009
• Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB. 13 Nov 2009
• The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms. 13 Nov 2009
• Establishing legitimacy and function in the new transcriptome. 30 Oct 2009
• Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells. 30 Oct 2009
• Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation. 30 Oct 2009
• Cytokines and signaling pathways regulating matrix metalloproteinase-9 (MMP-9) expression in corneal epithelial cells. 30 Oct 2009
• The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction. 21 Oct 2009
• Seed storage protein gene promoters contain conserved DNA motifs in Brassicaceae, Fabaceae and Poaceae. 18 Oct 2009
• Structure and inhibition of human diamine oxidase. 18 Oct 2009
• Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization. 18 Oct 2009
• Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production. 16 Oct 2009
• Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2. 16 Oct 2009
• AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. 14 Oct 2009
• Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition. 13 Oct 2009
• Promoter recognition by bacterial alternative sigma factors: the price of high selectivity? 13 Oct 2009

See a longer list of these articles.

Technical information about 'Promoter Regions, Genetic'

Definition: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.

Descriptor UI: D011401

Alternative terms: Promoter Regions, Genetic; Genetic Promoter Region; Genetic Promoter Regions; Promoter Region, Genetic; Region, Genetic Promoter; Regions, Genetic Promoter; Promoter Regions; Promoter Region; Region, Promoter; Regions, Promoter; Promotor Regions; Promotor Region; Region, Promotor; Regions, Promotor; Late Promoters, Genetic; Genetic Late Promoter; Late Promoter, Genetic; Middle Promoters, Genetic; Genetic Middle Promoters; Middle Promoter, Genetic; Promoters, Genetic Middle; rRNA Promoter; Promoter, rRNA; Promoters, rRNA; rRNA Promoters; Promoter, Genetic; Genetic Promoter; Genetic Promoters; Promoters, Genetic; Promotor, Genetic; Genetic Promotor; Genetic Promotors; Promotors, Genetic; Pseudopromoter, Genetic; Genetic Pseudopromoter; Genetic Pseudopromoters; Pseudopromoters, Genetic; Early Promoters, Genetic; Early Promoter, Genetic; Promoter, Genetic Early;

Related Mesh Headings: Genes, Reporter;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.570.080.689.675; G05.360.080.689.675; G05.360.340.024.340.137.750.680;

History Note: 2009 (1985); for PROMOTER, GENETIC use OPERON 1980-1984; for rRNA PROMOTER use rRNA OPERON 1990-1998