Propofol - Administration & dosage
Research News and Information

Tuesday, November 24, 2009

Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study).

30 Oct 2009 BACKGROUND: Commonly used sedatives/analgesics can increase the risk of postoperative complications, including delirium. This double-blinded study assessed the neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine compared ... Read more...

Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure.

13 Oct 2009 Propofol is a potent and widely used central-acting sedative drug. It has been implicated in the development of a usually fatal syndrome characterized by metabolic acidosis, rhabdomyolysis, ventricular arrhythmia, and Brugada-like cardiac rhythm ... Read more...

[Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation]

30 Aug 2009 BACKGROUND: As we have no information whether target-controlled infusion (TCI) for propofol, using pharmacokinetic parameters obtained without chronic renal failure, is available to estimate the drug concentration, we examined the blood ... Read more...

Latest indexed articles for 'Propofol - Administration & dosage'

These are the very latest articles for this heading:

• Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study). 30 Oct 2009
• Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure. 13 Oct 2009
• [Nurse administered propofol sedation in connection with endoscopy] 12 Sep 2009
• [Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation] 30 Aug 2009
• The use of fospropofol during bronchoscopy. 30 Aug 2009
• Automated responsiveness monitor to titrate propofol sedation. 30 Aug 2009
• A comparison of dexmedetomidine with propofol for magnetic resonance imaging sleep studies in children. 30 Aug 2009
• Comparison of the EasyTube and endotracheal tube during general anesthesia in fasted adult patients. 20 Aug 2009
• [Nurse administered propofol sedation in connection with endoscopy] 15 Aug 2009
• Bispectral index-monitored anesthesia technique for transsternal thymectomy. 30 Jul 2009
• Frontal lobe oxygenation is maintained during hypotension following propofol-fentanyl anesthesia. 30 Jul 2009
• Safe practices for propofol infusion. 30 Jul 2009
• Experience of intravenous sedation for pediatric gastrointestinal endoscopy in a large tertiary referral center in a developing country. 30 Jul 2009
• Effect of administration of propofol and xylazine hydrochloride on recovery of horses after four hours of anesthesia with desflurane. 30 Jul 2009
• Prolonged propofol anesthesia is not associated with an increase in blood lactate. 27 Jul 2009
• Early cognitive impairment after sedation for colonoscopy: the effect of adding midazolam and/or fentanyl to propofol. 15 Jul 2009
• Ventricular rhythm in atrial fibrillation under anaesthetic infusion with propofol. 8 Jul 2009
• Anaesthetic and cardiorespiratory effects of propofol at 10% for induction and 1% for maintenance of anaesthesia in horses. 29 Jun 2009
• Paravertebral block in inguinal hernia surgeries: two segments or 4 segments? 29 Jun 2009
• [Effects of the injection method of lidocaine on preventing injection pain during anesthesia induction by target controlled infusion with propofol] 29 Jun 2009

See a longer list of these articles.

Technical information about 'Propofol'

Definition: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

Chemical name: Phenol, 2,6-bis(1-methylethyl)-

Registry Number: 2078-54-8

Descriptor UI: D015742

Alternative terms: Propofol; 2,6-Diisopropylphenol; 2,6 Diisopropylphenol; Disoprofol; 2,6-Bis(1-methylethyl)phenol; Diprivan; Zeneca Brand of Propofol; Disoprivan; Astra Brand of Propofol; AstraZeneca Brand of Propofol; Fresofol; Alpha Brand of Propofol; ICI-35,868; ICI 35,868; ICI35,868; ICI-35868; ICI 35868; ICI35868; Recofol; Pisa Brand of Propofol; Schering Brand of Propofol; Curamed Brand of Propofol; Propofol Abbott; Abbott Brand of Propofol; Propofol Fresenius; Fresenius Kabi Brand of Propofol; Propofol MCT; Fresenius Brand of Propofol; Propofol Rovi; Rovi Brand of Propofol; Propofol-Lipuro; Braun Brand of Propofol; Aquafol; Parnell Brand of Propofol; Ivofol; Juste Brand of Propofol;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anesthetics, Intravenous; Hypnotics and Sedatives;

Tree Number: D02.755.773;

History Note: 90