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Propofol - Adverse effects
Research News and Information
Definition of 'Propofol'An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS. Common names: Propofol; 2,6-Diisopropylphenol; 2,6 Diisopropylphenol; Disoprofol; 2,6-Bis(1-methylethyl)phenol; Diprivan; Zeneca Brand of Propofol; Disoprivan; Astra Brand of Propofol; AstraZeneca Brand of Propofol; Fresofol; Alpha Brand of Propofol; ICI-35,868; ICI 35,868; ICI35,868; ICI-35868; ICI 35868 |
Monday, November 23, 2009
Prolonged myoclonus after a single bolus dose of propofol.
30 Oct 2009 
Propofol is a commonly used anaesthetic agent and is rarely associated with seizure-like phenomena. This case report presents a young woman with seizure-like phenomena lasting more than 4 weeks after a single dose of propofol. The underlying ... Read more...
Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure.
13 Oct 2009 Propofol is a potent and widely used central-acting sedative drug. It has been implicated in the development of a usually fatal syndrome characterized by metabolic acidosis, rhabdomyolysis, ventricular arrhythmia, and Brugada-like cardiac rhythm ... Read more...
New drug, fospropofol disodium: a propofol prodrug.
30 Jul 2009 The use of propofol presents chemical and clinical concerns, including pain on injection, allergy risks, possible bacteria growth, and hyperlipidemia. These concerns have encouraged the search for alternative propofol formulations. Elimination of ... Read more...
Latest indexed articles for 'Propofol - Adverse effects'
These are the very latest articles for this heading:
- Prolonged myoclonus after a single bolus dose of propofol. 30 Oct 2009
- Green breast milk after propofol administration.
30 Oct 2009 - Methohexital and propofol in ambulatory procedures. 30 Oct 2009
- Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure. 13 Oct 2009
- The safety of propofol. 4 Oct 2009
- Non-acidotic propofol infusion syndrome. 29 Sep 2009
- Concerns mount over misuse of anaesthetic propofol among US health professionals. 6 Sep 2009
- Sedation and drugs in pediatric patients: what is new? 30 Aug 2009
- The use of fospropofol during bronchoscopy. 30 Aug 2009
- New drug, fospropofol disodium: a propofol prodrug. 30 Jul 2009
- Frontal lobe oxygenation is maintained during hypotension following propofol-fentanyl anesthesia. 30 Jul 2009
- Experience of intravenous sedation for pediatric gastrointestinal endoscopy in a large tertiary referral center in a developing country. 30 Jul 2009
- Evaluation of DNA damage and lipoperoxidation of propofol in patients undergoing elective surgery. 30 Jul 2009
- The effects of propofol infusion on hepatic and pancreatic function and acid-base status in children undergoing craniotomy and receiving phenytoin.
30 Jul 2009 - Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk? 30 Jul 2009
- Prolonged propofol anesthesia is not associated with an increase in blood lactate. 27 Jul 2009
- Early cognitive impairment after sedation for colonoscopy: the effect of adding midazolam and/or fentanyl to propofol. 15 Jul 2009
- Pharmacology of commonly used analgesics and sedatives in the ICU: benzodiazepines, propofol, and opioids. 29 Jun 2009
- A comparison of the effects of desflurane, sevoflurane and propofol on QT, QTc, and P dispersion on ECG. 29 Jun 2009
- Cardiovascular manifestations of sedatives and analgesics in the critical care unit. 29 Jun 2009
See a longer list of these articles.
Technical information about 'Propofol'
Definition: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
Chemical name: Phenol, 2,6-bis(1-methylethyl)-
Registry Number: 2078-54-8
Descriptor UI: D015742
Alternative terms: Propofol; 2,6-Diisopropylphenol; 2,6 Diisopropylphenol; Disoprofol; 2,6-Bis(1-methylethyl)phenol; Diprivan; Zeneca Brand of Propofol; Disoprivan; Astra Brand of Propofol; AstraZeneca Brand of Propofol; Fresofol; Alpha Brand of Propofol; ICI-35,868; ICI 35,868; ICI35,868; ICI-35868; ICI 35868; ICI35868; Recofol; Pisa Brand of Propofol; Schering Brand of Propofol; Curamed Brand of Propofol; Propofol Abbott; Abbott Brand of Propofol; Propofol Fresenius; Fresenius Kabi Brand of Propofol; Propofol MCT; Fresenius Brand of Propofol; Propofol Rovi; Rovi Brand of Propofol; Propofol-Lipuro; Braun Brand of Propofol; Aquafol; Parnell Brand of Propofol; Ivofol; Juste Brand of Propofol;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Pharmacological Action: Anesthetics, Intravenous; Hypnotics and Sedatives;
Tree Number: D02.755.773;
History Note: 90