Propofol
Research News and Information

Sunday, November 22, 2009

Prolonged myoclonus after a single bolus dose of propofol.

30 Oct 2009 Propofol is a commonly used anaesthetic agent and is rarely associated with seizure-like phenomena. This case report presents a young woman with seizure-like phenomena lasting more than 4 weeks after a single dose of propofol. The underlying ... Read more...

Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study).

30 Oct 2009 BACKGROUND: Commonly used sedatives/analgesics can increase the risk of postoperative complications, including delirium. This double-blinded study assessed the neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine compared ... Read more...

Propofol inhibits aquaporin 4 expression through a protein kinase C-dependent pathway in an astrocyte model of cerebral ischemia/reoxygenation.

30 Oct 2009 BACKGROUND: Aquaporin 4 (AQP4) plays a key role in maintaining water balance in the central nervous system, and its dysfunction may lead to brain edema. Previous studies have suggested that propofol may be involved in neuroprotection by preventing ... Read more...

Latest indexed articles for 'Propofol'

These are the very latest articles for this heading:

• Prolonged myoclonus after a single bolus dose of propofol. 30 Oct 2009
• Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study). 30 Oct 2009
• Green breast milk after propofol administration. 30 Oct 2009
• Propofol inhibits aquaporin 4 expression through a protein kinase C-dependent pathway in an astrocyte model of cerebral ischemia/reoxygenation. 30 Oct 2009
• The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion. 30 Oct 2009
• The effects of sevoflurane and propofol on glucose metabolism under aerobic conditions in fed rats. 30 Oct 2009
• Methohexital and propofol in ambulatory procedures. 30 Oct 2009
• Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure. 13 Oct 2009
• Schedule of controlled substances; placement of fospropofol into schedule IV. Final rule. 4 Oct 2009
• The safety of propofol. 4 Oct 2009
• Non-acidotic propofol infusion syndrome. 29 Sep 2009
• [Nurse administered propofol sedation in connection with endoscopy] 12 Sep 2009
• Concerns mount over misuse of anaesthetic propofol among US health professionals. 6 Sep 2009
• [Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation] 30 Aug 2009
• Effects of propofol or etomidate on QT interval during electroconvulsive therapy. 30 Aug 2009
• Perioperative recommendations in a child with Fish Odor syndrome. 30 Aug 2009
• Sedation and drugs in pediatric patients: what is new? 30 Aug 2009
• Facilitation of glutamate release from rat cerebral cortex nerve terminal by subanesthetic concentration propofol. 30 Aug 2009
• The use of fospropofol during bronchoscopy. 30 Aug 2009
• Effects of remifentanil on the spectrum and quantitative parameters of electroencephalogram in propofol anesthesia. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Propofol'

Definition: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

Chemical name: Phenol, 2,6-bis(1-methylethyl)-

Registry Number: 2078-54-8

Descriptor UI: D015742

Alternative terms: Propofol; 2,6-Diisopropylphenol; 2,6 Diisopropylphenol; Disoprofol; 2,6-Bis(1-methylethyl)phenol; Diprivan; Zeneca Brand of Propofol; Disoprivan; Astra Brand of Propofol; AstraZeneca Brand of Propofol; Fresofol; Alpha Brand of Propofol; ICI-35,868; ICI 35,868; ICI35,868; ICI-35868; ICI 35868; ICI35868; Recofol; Pisa Brand of Propofol; Schering Brand of Propofol; Curamed Brand of Propofol; Propofol Abbott; Abbott Brand of Propofol; Propofol Fresenius; Fresenius Kabi Brand of Propofol; Propofol MCT; Fresenius Brand of Propofol; Propofol Rovi; Rovi Brand of Propofol; Propofol-Lipuro; Braun Brand of Propofol; Aquafol; Parnell Brand of Propofol; Ivofol; Juste Brand of Propofol;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anesthetics, Intravenous; Hypnotics and Sedatives;

Tree Number: D02.755.773;

History Note: 90