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Protein Binding
Research News and Information
Definition of 'Protein Binding'The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. Common names: Protein Binding; Binding, Protein; Plasma Protein Binding Capacity |
Saturday, November 21, 2009
29 Nov 2009 
The nuclear protein methyl-transferase Retinoblastoma-interacting zinc-finger protein 1 (RIZ1) is considered to be a downstream effector of estrogen action in target tissues. Silencing of RIZ1 expression is common in many tumors. We analyzed RIZ1 ... Read more...
29 Nov 2009 The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of ... Read more...
29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...
Latest indexed articles for 'Protein Binding'
These are the very latest articles for this heading:
- Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. 29 Nov 2009
- Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. 29 Nov 2009
- Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
- Requirement of a dynein light chain in TGFbeta/Smad3 signaling. 29 Nov 2009
- Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1. 29 Nov 2009
- p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. 29 Nov 2009
- Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex. 18 Nov 2009
- PilM/N/O/P proteins form an inner membrane complex that affects the stability of the Pseudomonas aeruginosa type IV pilus secretin. 18 Nov 2009
- The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. 13 Nov 2009
- Requirement of a unique Ca(2+)-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon. 8 Nov 2009
- A novel domain in translational GTPase BipA mediates interaction with the 70S ribosome and influences GTP hydrolysis. 8 Nov 2009
- Single-molecule dynamics of the DNA-EcoRII protein complexes revealed with high-speed atomic force microscopy. 8 Nov 2009
- Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain. 8 Nov 2009
- Mechanisms of interactions of the nucleotide cofactor with the RepA protein of plasmid RSF1010. Binding dynamics studied using the fluorescence stopped-flow method. 8 Nov 2009
- Solution structure and functional characterization of human plasminogen kringle 5. Nov 2009
- GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions. Nov 2009
- Characterization and structure of the manganese-responsive transcriptional regulator ScaR. Nov 2009
- Single crystal structural and absorption spectral characterizations of nitric oxide synthase complexed with N(omega)-hydroxy-L-arginine and diatomic ligands. Nov 2009
- Redox characterization of the FeS protein MitoNEET and impact of thiazolidinedione drug binding. Nov 2009
- Herpes simplex virus-1 helicase-primase: roles of each subunit in DNA binding and phosphodiester bond formation. Nov 2009
See a longer list of these articles.
Technical information about 'Protein Binding'
Definition: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Descriptor UI: D011485
Alternative terms: Protein Binding; Binding, Protein; Plasma Protein Binding Capacity;
Related Mesh Headings: Binding Sites; Carrier Proteins; Metalloproteins; Radioligand Assay; Thyroxine-Binding Proteins;
Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;
Tree Number: G02.111.087.680; G02.149.115.680; G03.495.800;
History Note: 70(66)
Technical Notes: NIM; restrict to the chem or metab binding mechanism; coord NIM with substance being bound /metab (IM) + specific protein /metab (IM); do not use with receptors terms unless the substance bound to the receptor is a protein & the binding mechanism is discussed; do not confuse with BINDING PROTEINS see CARRIER PROTEINS