Protein Conformation
Research News and Information

Monday, November 23, 2009

The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp.

21 Dec 2009 BACKGROUND: The JAL antigen (Rh48) was discovered more than 30 years ago when it caused hemolytic disease of the fetus and newborn in an African American family. A decade later it was found to cause hemolytic disease of the fetus and newborn in a ... Read more...

The DEAD box helicase YxiN maintains a closed conformation during ATP hydrolysis.

15 Nov 2009 DEAD box helicases unwind RNA duplexes at the expense of ATP hydrolysis. Recently, unwinding has been demonstrated in the absence of ATP hydrolysis. Herein, we show that ADP.BeF(x) supports RNA unwinding by YxiN, a DEAD box helicase that ... Read more...

Helix formation in arrestin accompanies recognition of photoactivated rhodopsin.

15 Nov 2009 Binding of arrestin to photoactivated phosphorylated rhodopsin terminates the amplification of visual signals in photoreceptor cells. Currently, there is no crystal structure of a rhodopsin-arrestin complex available, although structures of unbound ... Read more...

Latest indexed articles for 'Protein Conformation'

These are the very latest articles for this heading:

• The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp. 21 Dec 2009
• The DEAD box helicase YxiN maintains a closed conformation during ATP hydrolysis. 15 Nov 2009
• Helix formation in arrestin accompanies recognition of photoactivated rhodopsin. 15 Nov 2009
• IspG enzyme activity in the deoxyxylulose phosphate pathway: roles of the iron-sulfur cluster. 8 Nov 2009
• Requirement of a unique Ca(2+)-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon. 8 Nov 2009
• Structural basis for the lack of E2 interaction in the RING domain of TRAF2. 8 Nov 2009
• Identification and characterization of binding sites on S100A7, a participant in cancer and inflammation pathways. 8 Nov 2009
• Sortase activity is controlled by a flexible lid in the pilus biogenesis mechanism of gram-positive pathogens. 8 Nov 2009
• Hybrid quantum/classical molecular dynamics simulations of the proton transfer reactions catalyzed by ketosteroid isomerase: analysis of hydrogen bonding, conformational motions, and electrostatics. 8 Nov 2009
• Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. 2 Nov 2009
• Monomer-dimer equilibrium in glutathione transferases: a critical re-examination. Nov 2009
• Role of tryptophan-tryptophan interactions in Trpzip beta-hairpin formation, structure, and stability. Nov 2009
• Biophysical characterization of Chlamydia trachomatis CT584 supports its potential role as a type III secretion needle tip protein. Nov 2009
• Predicting structurally conserved contacts for homologous proteins using sequence conservation filters. 30 Oct 2009
• Targeted molecular dynamics reveals overall common conformational changes upon hybrid domain swing-out in beta3 integrins. 30 Oct 2009
• Quantitative analysis and prediction of curvature in leucine-rich repeat proteins. 30 Oct 2009
• Combining interface core and whole interface descriptors in postscan processing of protein-protein docking models. 30 Oct 2009
• Native state dynamics and mechanical properties of human topoisomerase I within a structure-based coarse-grained model. 30 Oct 2009
• Temperature-induced partially unfolded state of hUBF HMG Box-5: conformational and dynamic investigations of the Box-5 thermal intermediate ensemble. 30 Oct 2009
• A distance-dependent atomic knowledge-based potential and force for discrimination of native structures from decoys. 30 Oct 2009

See a longer list of these articles.

Technical information about 'Protein Conformation'

Definition: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).

Descriptor UI: D011487

Alternative terms: Protein Conformation; Conformation, Protein; Conformations, Protein; Protein Conformations;

Allowable Qualifiers: drug effects; radiation effects;

Tree Number: G02.111.570.790.709;

History Note: 72

Technical Notes: IM general; coord NIM with specific protein; peptide conformation = PEPTIDES or specific peptide (IM) + PROTEIN CONFORMATION (NIM); index protein architecture here or under its specifics