Protein Processing, Post-Translational
Research News and Information

Monday, November 23, 2009

Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor.

13 Dec 2009 We describe an infant with cytomegalovirus (CMV) infection presenting as transient myeloproliferation resembling juvenile myelomonocytic leukemia (JMML). The patient fulfilled the international diagnostic criteria of JMML, including hypersensitivity ... Read more...

The emerging characterization of lysine residue deacetylation on the modulation of mitochondrial function and cardiovascular biology.

21 Oct 2009 There is emerging recognition of a novel fuel and redox sensing regulatory program that controls cellular adaptation via nonhistone protein lysine residue acetyl posttranslation modifications. This program functions in tissues with high energy ... Read more...

A coming-of-age story: activation-induced cytidine deaminase turns 10.

18 Oct 2009 The discovery and characterization of activation-induced cytidine deaminase (AID) 10 years ago provided the basis for a mechanistic understanding of secondary antibody diversification and the subsequent generation and maintenance of cellular memory ... Read more...

Latest indexed articles for 'Protein Processing, Post-Translational'

These are the very latest articles for this heading:

• Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor. 13 Dec 2009
• The emerging characterization of lysine residue deacetylation on the modulation of mitochondrial function and cardiovascular biology. 21 Oct 2009
• A coming-of-age story: activation-induced cytidine deaminase turns 10. 18 Oct 2009
• Nutrient isothiocyanates covalently modify and inhibit the inflammatory cytokine macrophage migration inhibitory factor (MIF). 10 Oct 2009
• Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. 4 Oct 2009
• No way out for tumor cells. 4 Oct 2009
• Regulating the regulators: posttranslational modifications of RNA silencing factors. 30 Sep 2009
• Learning how to read ADP-ribosylation. 30 Sep 2009
• PORE-ing over ERK substrates. 29 Sep 2009
• Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions. 29 Sep 2009
• Posttranscriptional and posttranslational determinants of cyclooxygenase expression. 28 Sep 2009
• Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics. 27 Sep 2009
• Titin phosphorylation: myocardial passive stiffness regulated by the intracellular giant. 23 Sep 2009
• Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions. 23 Sep 2009
• Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda. 23 Sep 2009
• Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. 22 Sep 2009
• Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes. 22 Sep 2009
• Destruction of RhoA CULtivates actin. 22 Sep 2009
• Summon SUMO to wrestle with inflammation. 22 Sep 2009
• Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2. 22 Sep 2009

See a longer list of these articles.

Technical information about 'Protein Processing, Post-Translational'

Definition: Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.

Descriptor UI: D011499

Alternative terms: Protein Processing, Post-Translational; Processing, Post-Translational Protein; Post-Translational Protein Processing; Post Translational Protein Processing; Protein Processing, Post Translational; Protein Modification, Post-Translational; Protein Modification, Post Translational; Protein Processing, Posttranslational; Posttranslational Modifications; Modification, Posttranslational; Modifications, Posttranslational; Posttranslational Modification; Post-Translational Modifications; Modification, Post-Translational; Modifications, Post-Translational; Post Translational Modifications; Post-Translational Modification; Post-Translational Protein Modification; Modification, Post-Translational Protein; Modifications, Post-Translational Protein; Post Translational Protein Modification; Post-Translational Protein Modifications; Protein Modifications, Post-Translational; Posttranslational Protein Processing; Processing, Posttranslational Protein; Amino Acid Modification, Post-Translational; Amino Acid Modification, Post Translational; Posttranslational Amino Acid Modification; Amino Acid Modification, Posttranslational; Post-Translational Amino Acid Modification; Post Translational Amino Acid Modification;

Related Mesh Headings: Histone Code;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.087.675.871.790.600; G02.111.087.693.600; G02.149.115.675.871.790.600; G02.149.115.693.600; G03.495.770.871.790.600; G05.355.315.670.600;

History Note: 83

Technical Notes: coord IM with specific protein /metab (IM) and with specific modification, for example, ACYLATION; AMINATION; DEAMINATION; PROTEIN ISOPRENYLATION; etc.; do not confuse with PROTEIN MODIFICATION, TRANSLATIONAL; DF: PROTEIN PROC POST