Protein Transport
Research News and Information

Sunday, November 22, 2009

Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells.

29 Nov 2009 Bradykinin (BK) is a potent modulator of biological processes in the retina, and retinal pigment epithelial cells (RPE) and the regulation of glutamate are believed to be important in the pathogenesis of diabetic retinopathy. However, the mechanism ... Read more...

Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

29 Nov 2009 The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of ... Read more...

Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval.

29 Nov 2009 ClC-2 chloride channel is present in the brain and some transporting epithelia where its function is poorly understood. We have now demonstrated that the surface channels are rapidly internalised and approximately the 70% of the surface membrane ... Read more...

Latest indexed articles for 'Protein Transport'

These are the very latest articles for this heading:

• Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells. 29 Nov 2009
• Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. 29 Nov 2009
• Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval. 29 Nov 2009
• PilM/N/O/P proteins form an inner membrane complex that affects the stability of the Pseudomonas aeruginosa type IV pilus secretin. 18 Nov 2009
• A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection. 2 Nov 2009
• The periplasmic chaperone Skp facilitates targeting, insertion, and folding of OmpA into lipid membranes with a negative membrane surface potential. Nov 2009
• The membrane topography of the diphtheria toxin T domain linked to the a chain reveals a transient transmembrane hairpin and potential translocation mechanisms. Nov 2009
• NF-kappaB independent activation of a series of proinflammatory genes by hydrogen sulfide. 30 Oct 2009
• Leptin attenuates hypoxia/reoxygenation-induced activation of the intrinsic pathway of apoptosis in rat H9c2 cells. 30 Oct 2009
• CXCL14 inhibits trophoblast outgrowth via a paracrine/autocrine manner during early pregnancy in mice. 30 Oct 2009
• RAGE expression and NF-kappaB activation attenuated by extracellular domain of RAGE in human salivary gland cell line. 30 Oct 2009
• Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms. 30 Oct 2009
• E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells. 30 Oct 2009
• Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. 27 Oct 2009
• Intra-axonal patterning: intrinsic compartmentalization of the axonal membrane in Drosophila neurons. 27 Oct 2009
• SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. 27 Oct 2009
• Sun proteins enlighten nuclear movement in development. 27 Oct 2009
• Analysis of the dual function of the ESCRT-III protein Snf7 in endocytic trafficking and in gene expression. 21 Oct 2009
• The TC10-Exo70 complex is essential for membrane expansion and axonal specification in developing neurons. 19 Oct 2009
• Schizophrenia: the "BLOC" may be in the endosomes. 18 Oct 2009

See a longer list of these articles.

Technical information about 'Protein Transport'

Definition: The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.

Descriptor UI: D021381

Alternative terms: Protein Transport; Protein Transports; Protein Trafficking; Protein Traffickings; Trafficking, Protein; Traffickings, Protein; Gated Protein Transport; Protein Transport, Gated; Protein Targeting; Targeting, Protein; Protein Localization Processes, Cellular; Protein Translocation; Transmembrane Protein Transport; Protein Transport, Transmembrane; Transmembrane Protein Transports; Vesicular Protein Transport; Protein Transport, Vesicular; Protein Sorting; Protein Sortings;

Related Mesh Headings: Protein Sorting Signals;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G03.495.166.700;

History Note: 2001

Technical Notes: coordinate NIM with specific protein/metab (IM) or /pharmacokin (IM)