Proto-Oncogene Proteins c-fos - Drug effects
Research News and Information

Saturday, November 21, 2009

Induction of MMP-1 (collagenase-1) by relaxin in fibrocartilaginous cells requires both the AP-1 and PEA-3 promoter sites.

30 Jul 2009 OBJECTIVES - Relaxin induces the matrix metalloproteinase MMP-1 (collagenase-1) in TMJ fibrocartilaginous cells, and this response is potentiated by beta-estradiol. We identified the MMP-1 promoter sites and transcription factors that are induced by ... Read more...

Evidence for a role of NTS2 receptors in the modulation of tonic pain sensitivity.

4 Jul 2009 BACKGROUND: Central neurotensin (NT) administration results in a naloxone-insensitive antinociceptive response in animal models of acute and persistent pain. Both NTS1 and NTS2 receptors were shown to be required for different aspects of NT-induced ... Read more...

GABAergic antagonism of the central nucleus of the amygdala attenuates reductions in rapid eye movement sleep after inescapable footshock stress.

29 Jun 2009 STUDY OBJECTIVES: Rapid eye movement sleep (REM) appears to be especially susceptible to the effects of stress; inescapable footshock stress (IS) can produce reductions in REM that can occur without recovery sleep. The amygdala has well-established ... Read more...

Latest indexed articles for 'Proto-Oncogene Proteins c-fos - Drug effects'

These are the very latest articles for this heading:

• Induction of MMP-1 (collagenase-1) by relaxin in fibrocartilaginous cells requires both the AP-1 and PEA-3 promoter sites. 30 Jul 2009
• Evidence for a role of NTS2 receptors in the modulation of tonic pain sensitivity. 4 Jul 2009
• GABAergic antagonism of the central nucleus of the amygdala attenuates reductions in rapid eye movement sleep after inescapable footshock stress. 29 Jun 2009
• "Green odor" inhalation by rats down-regulates stress-induced increases in Fos expression in stress-related forebrain regions. 25 Jun 2009
• Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. 12 May 2009
• Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats. 20 Apr 2009
• The immediate early genes, c-fos, c-jun and AP-1, are early markers of platinum analogue toxicity in human proximal tubular cell primary cultures. 17 Apr 2009
• TNF activates astrocytes and catecholaminergic neurons in the solitary nucleus: implications for autonomic control. 3 Apr 2009
• Bidirectional regulation of stress responses by galanin in mice: involvement of galanin receptor subtype 1. 7 Mar 2009
• N-methyl-D-aspartate and sigma-ligands change the production of interleukins 8 and 10 in lymphocytes through modulation of the NMDA glutamate receptor. 22 Feb 2009
• Dopamine D1 receptor, but not dopamine D2 receptor, is a critical regulator for acute cocaine-enhanced gene expression. 30 Jan 2009
• Characterization of parabrachial subnuclei in mice with regard to salt tastants: possible independence of taste relay from visceral processing. 27 Jan 2009
• An immunohistochemical study of the antinociceptive effect of calcitonin in ovariectomized rats. 13 Dec 2008
• Chronic methylphenidate treatment enhances striatal dopamine neurotransmission after experimental traumatic brain injury. 8 Dec 2008
• Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway. 29 Nov 2008
• Effects of isorhynchophylline on angiotensin II-induced proliferation in rat vascular smooth muscle cells. 29 Nov 2008
• The effect of Ginkgo biloba on the expression of intermediate-early antigen (c-fos) in the experimentally induced anosmic mouse. 15 Nov 2008
• Acute and sensitized response to 3,4-methylenedioxymethamphetamine in rats: different behavioral profiles reflected in different patterns of Fos expression. 30 Oct 2008
• Uncoupling of interleukin-6 from its signalling pathway by dietary n-3-polyunsaturated fatty acid deprivation alters sickness behaviour in mice. 30 Oct 2008
• NMDA antagonist and antipsychotic actions in cortico-subcortical circuits. 29 Sep 2008

See a longer list of these articles.

Technical information about 'Proto-Oncogene Proteins c-fos'

Definition: Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.

Registry Number: 0

Descriptor UI: D016760

Alternative terms: Proto-Oncogene Proteins c-fos; Proto Oncogene Proteins c fos; fos Proto-Oncogene Proteins; fos Proto Oncogene Proteins; Proto-Oncogene Proteins fos; Proto Oncogene Proteins fos; p55(c-fos); Proto-Oncogene Products c-fos; Proto Oncogene Products c fos; c-fos Proteins; c fos Proteins; p55 c-fos; p55 c fos; Fos B Protein; Antigens, Fos-Related; FRAs; Fos-Related Antigens; Fos Related Antigens;

Related Mesh Headings: Transcription Factor AP-1;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.108.765; D12.776.624.664.700.179; D12.776.660.760; D12.776.930.127.765;

Online Note: use PROTO-ONCOGENE PROTEINS C-FOS (NM) to search PROTO-ONCOGENE PROTEIN FOS (NM) 1985-91 & FOS B PROTEIN (NM) 1990-91

History Note: 92; was PROTO-ONCOGENE PROTEIN FOS (NM) 1985-91; FOS B PROTEIN was FOS B PROTEIN (NM) 1990-91

Technical Notes: /drug eff /ultrastruct permitted; not for c-fos 39 ( = C-FOS-ASSOCIATED PROTEIN P39 see PROTO-ONCOGENE PROTEINS C-JUN); DF: note short X refs