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Proto-Oncogene Proteins c-fos - Genetics
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Definition of 'Proto-Oncogene Proteins c-fos'

Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.

Common names: Proto-Oncogene Proteins c-fos; Proto Oncogene Proteins c fos; fos Proto-Oncogene Proteins; fos Proto Oncogene Proteins; Proto-Oncogene Proteins fos; Proto Oncogene Proteins fos; p55(c-fos); Proto-Oncogene Products c-fos; Proto Oncogene Products c fos; c-fos Proteins; c fos Proteins; p55 c-fos

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Sunday, November 22, 2009

Exaggerated response of a vasopressin-enhanced green fluorescent protein transgene to nociceptive stimulation in the rat.

19 Oct 2009 Nociceptive stimulation elicits neuroendocrine responses such as arginine vasopressin (AVP) release as well as activation of the hypothalamo-pituitary-adrenal axis. We have generated novel transgenic rats expressing an AVP-enhanced green fluorescent ... Read more...


Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription.

5 Oct 2009 cAMP can stimulate the transcription of many activity-dependent genes via activation of the transcription factor, cAMP response element-binding protein (CREB). However, in mouse cortical neuron cultures, prior to synaptogenesis, neither cAMP nor ... Read more...


c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues.

29 Sep 2009 The capability of cocaine cues to generate craving in cocaine-dependent humans, even after extended abstinence, is modeled in rats using cue reinstatement of extinguished cocaine-seeking behavior. We investigated neural activity associated with ... Read more...

 

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Technical information about 'Proto-Oncogene Proteins c-fos'

Definition: Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.

Registry Number: 0

Descriptor UI: D016760

Alternative terms: Proto-Oncogene Proteins c-fos; Proto Oncogene Proteins c fos; fos Proto-Oncogene Proteins; fos Proto Oncogene Proteins; Proto-Oncogene Proteins fos; Proto Oncogene Proteins fos; p55(c-fos); Proto-Oncogene Products c-fos; Proto Oncogene Products c fos; c-fos Proteins; c fos Proteins; p55 c-fos; p55 c fos; Fos B Protein; Antigens, Fos-Related; FRAs; Fos-Related Antigens; Fos Related Antigens;

Related Mesh Headings: Transcription Factor AP-1;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.108.765; D12.776.624.664.700.179; D12.776.660.760; D12.776.930.127.765;

Online Note: use PROTO-ONCOGENE PROTEINS C-FOS (NM) to search PROTO-ONCOGENE PROTEIN FOS (NM) 1985-91 & FOS B PROTEIN (NM) 1990-91

History Note: 92; was PROTO-ONCOGENE PROTEIN FOS (NM) 1985-91; FOS B PROTEIN was FOS B PROTEIN (NM) 1990-91

Technical Notes: /drug eff /ultrastruct permitted; not for c-fos 39 ( = C-FOS-ASSOCIATED PROTEIN P39 see PROTO-ONCOGENE PROTEINS C-JUN); DF: note short X refs

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