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Proto-Oncogene Proteins c-fos
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Definition of 'Proto-Oncogene Proteins c-fos'

Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.

Common names: Proto-Oncogene Proteins c-fos; Proto Oncogene Proteins c fos; fos Proto-Oncogene Proteins; fos Proto Oncogene Proteins; Proto-Oncogene Proteins fos; Proto Oncogene Proteins fos; p55(c-fos); Proto-Oncogene Products c-fos; Proto Oncogene Products c fos; c-fos Proteins; c fos Proteins; p55 c-fos

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Saturday, November 21, 2009

Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents.

30 Oct 2009 BACKGROUND: One underexploited property of anesthetics is their ability to probe neuronal regulation of arousal. At appropriate doses, anesthetics reversibly obtund conscious perception. However, individual anesthetic agents may accomplish this by ... Read more...


The effect of a thoracic spinal block on fos expression in the lumbar spinal cord of the rat induced by a noxious electrical stimulus at the hindpaw.

30 Oct 2009 BACKGROUND: Fos expression in the lumbar spinal cord, resulting from a noxious electrical stimulus at the hindpaw, is hypothesized to originate from three sources: direct sensory input of the noxious stimulus, local interactions in the spinal cord, ... Read more...


Exaggerated response of a vasopressin-enhanced green fluorescent protein transgene to nociceptive stimulation in the rat.

19 Oct 2009 Nociceptive stimulation elicits neuroendocrine responses such as arginine vasopressin (AVP) release as well as activation of the hypothalamo-pituitary-adrenal axis. We have generated novel transgenic rats expressing an AVP-enhanced green fluorescent ... Read more...

 

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Technical information about 'Proto-Oncogene Proteins c-fos'

Definition: Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.

Registry Number: 0

Descriptor UI: D016760

Alternative terms: Proto-Oncogene Proteins c-fos; Proto Oncogene Proteins c fos; fos Proto-Oncogene Proteins; fos Proto Oncogene Proteins; Proto-Oncogene Proteins fos; Proto Oncogene Proteins fos; p55(c-fos); Proto-Oncogene Products c-fos; Proto Oncogene Products c fos; c-fos Proteins; c fos Proteins; p55 c-fos; p55 c fos; Fos B Protein; Antigens, Fos-Related; FRAs; Fos-Related Antigens; Fos Related Antigens;

Related Mesh Headings: Transcription Factor AP-1;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.108.765; D12.776.624.664.700.179; D12.776.660.760; D12.776.930.127.765;

Online Note: use PROTO-ONCOGENE PROTEINS C-FOS (NM) to search PROTO-ONCOGENE PROTEIN FOS (NM) 1985-91 & FOS B PROTEIN (NM) 1990-91

History Note: 92; was PROTO-ONCOGENE PROTEIN FOS (NM) 1985-91; FOS B PROTEIN was FOS B PROTEIN (NM) 1990-91

Technical Notes: /drug eff /ultrastruct permitted; not for c-fos 39 ( = C-FOS-ASSOCIATED PROTEIN P39 see PROTO-ONCOGENE PROTEINS C-JUN); DF: note short X refs

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