Pseudogenes
Research News and Information

Sunday, November 22, 2009

Comprehensive analysis of the pseudogenes of glycolytic enzymes in vertebrates: the anomalously high number of GAPDH pseudogenes highlights a recent burst of retrotrans-positional activity.

14 Oct 2009 BACKGROUND: Pseudogenes provide a record of the molecular evolution of genes. As glycolysis is such a highly conserved and fundamental metabolic pathway, the pseudogenes of glycolytic enzymes comprise a standardized genomic measuring stick and an ... Read more...

A comparison of reptilian and avian olfactory receptor gene repertoires: species-specific expansion of group gamma genes in birds.

19 Sep 2009 BACKGROUND: The detection of odorants is mediated by olfactory receptors (ORs). ORs are G-protein coupled receptors that form a remarkably large protein superfamily in vertebrate genomes. We used data that became available through recent sequencing ... Read more...

Assessing the genomic evidence for conserved transcribed pseudogenes under selection.

13 Sep 2009 BACKGROUND: Transcribed pseudogenes are copies of protein-coding genes that have accumulated indicators of coding-sequence decay (such as frameshifts and premature stop codons), but nonetheless remain transcribed. Recent experimental evidence ... Read more...

Latest indexed articles for 'Pseudogenes'

These are the very latest articles for this heading:

• Comprehensive analysis of the pseudogenes of glycolytic enzymes in vertebrates: the anomalously high number of GAPDH pseudogenes highlights a recent burst of retrotrans-positional activity. 14 Oct 2009
• A comparison of reptilian and avian olfactory receptor gene repertoires: species-specific expansion of group gamma genes in birds. 19 Sep 2009
• Assessing the genomic evidence for conserved transcribed pseudogenes under selection. 13 Sep 2009
• Implications of high level pseudogene transcription in Mycobacterium leprae. 23 Aug 2009
• Neural stem cells express Oct-3/4. 3 Aug 2009
• Brucella microti: the genome sequence of an emerging pathogen. 2 Aug 2009
• Small RNAs originated from pseudogenes: cis- or trans-acting? 29 Jul 2009
• Comparative sequence analysis of Mycobacterium leprae and the new leprosy-causing Mycobacterium lepromatosis. 22 Jul 2009
• A new CYP21A1P/CYP21A2 chimeric gene identified in an Italian woman suffering from classical congenital adrenal hyperplasia form. 20 Jul 2009
• Fusion and retrotransposition events in the evolution of the sea anemone Anemonia viridis neurotoxin genes. 14 Jul 2009
• Identification and characterization of pseudogenes in the rice gene complement. 14 Jul 2009
• Independent inactivation of arginine decarboxylase genes by nonsense and missense mutations led to pseudogene formation in Chlamydia trachomatis serovar L2 and D strains. 14 Jul 2009
• Genomic evidence for non-random endemic populations of decaying exons from mammalian genes. 11 Jul 2009
• Detection of RNA expression from pseudogenes and non-coding genomic regions of Mycobacterium leprae. 21 Jun 2009
• Evolutionary dynamics of recently duplicated genes: Selective constraints on diverging paralogs in the Drosophila pseudoobscura genome. 16 Jun 2009
• Fragments of the key flowering gene GIGANTEA are associated with helitron-type sequences in the Pooideae grass Lolium perenne. 5 Jun 2009
• Killer cell immunoglobulin-like receptor genotypes in Behçet's disease patients: any role for the 3DP1*001/002 pseudogene? 30 May 2009
• On the brink of holoparasitism: plastome evolution in dwarf mistletoes (Arceuthobium, Viscaceae). 27 May 2009
• Characterization of a putative hsp70 pseudogene transcribed in protoscoleces and adult worms of Echinococcus granulosus. 17 May 2009
• Functional evidence that the self-renewal gene NANOG regulates human tumor development. 29 Apr 2009

See a longer list of these articles.

Technical information about 'Pseudogenes'

Definition: Genes bearing close resemblance to known genes at different loci, but rendered non-functional by additions or deletions in structure that prevent normal transcription or translation. When lacking introns and containing a poly-A segment near the downstream end (as a result of reverse copying from processed nuclear RNA into double-stranded DNA), they are called processed genes.

Descriptor UI: D011544

Alternative terms: Pseudogenes; Pseudogene; Genes, Processed; Gene, Processed; Processed Gene; Processed Genes; beta-Tubulin Pseudogene; Pseudogene, beta-Tubulin; Pseudogenes, beta-Tubulin; beta Tubulin Pseudogene; beta-Tubulin Pseudogenes;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.360.340.024.340.700;

History Note: 88