Purkinje Cells - Physiology
Research News and Information

Saturday, November 21, 2009

AnkyrinG is required to maintain axo-dendritic polarity in vivo.

22 Sep 2009 Neurons are highly polarized cells that extend a single axon and several dendrites. Studies with cultured neurons indicate that the proximal portion of the axon, denoted as the axon initial segment (AIS), maintains neuronal polarity in vitro. The ... Read more...

Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum.

2 Sep 2009 In many parts of the vertebrate nervous system, synaptic connections are remodeled during early postnatal life. Neural activity plays an important role in regulating one such rearrangement, synapse elimination, in the developing neuromuscular ... Read more...

Differential expression of TrkB isoforms switches climbing fiber-Purkinje cell synaptogenesis to selective synapse elimination.

30 Aug 2009 Correct neural function depends on precisely organized connectivity, which is refined from broader projections through synaptic/collateral elimination. In the rat, olivocerebellar topography is refined by regression of multiple climbing fiber (CF) ... Read more...

Latest indexed articles for 'Purkinje Cells - Physiology'

These are the very latest articles for this heading:

• AnkyrinG is required to maintain axo-dendritic polarity in vivo. 22 Sep 2009
• Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum. 2 Sep 2009
• Differential expression of TrkB isoforms switches climbing fiber-Purkinje cell synaptogenesis to selective synapse elimination. 30 Aug 2009
• Reliable coding emerges from coactivation of climbing fibers in microbands of cerebellar Purkinje neurons. 24 Aug 2009
• Elimination of climbing fiber instructive signals during motor learning. 14 Aug 2009
• Ca currents activated by spontaneous firing and synaptic disinhibition in neurons of the cerebellar nuclei. 3 Aug 2009
• Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. 3 Aug 2009
• Eyeblink conditioning leads to fewer synapses in the rabbit cerebellar cortex. 30 Jul 2009
• Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration. 20 Jul 2009
• Submillisecond optical reporting of membrane potential in situ using a neuronal tracer dye. 20 Jul 2009
• Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. 20 Jul 2009
• Maximization of the connectivity repertoire as a statistical principle governing the shapes of dendritic arbors. 19 Jul 2009
• It's lonely at the top: winning climbing fibers ascend dendrites solo. 14 Jul 2009
• Rescue of abnormal phenotypes in delta2 glutamate receptor-deficient mice by the extracellular N-terminal and intracellular C-terminal domains of the delta2 glutamate receptor. 13 Jul 2009
• Large-conductance calcium-activated potassium channels in purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains. 8 Jul 2009
• Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning. 3 Jul 2009
• Principal cell spiking, postsynaptic excitation, and oxygen consumption in the rat cerebellar cortex. 29 Jun 2009
• Dopamine signaling is required for depolarization-induced slow current in cerebellar Purkinje cells. 29 Jun 2009
• The functional equivalence of ascending and parallel fiber inputs in cerebellar computation. 29 Jun 2009
• Effects of 1-naphthyl acetyl spermine on dendrite formation by cultured cerebellar Purkinje cells. 24 Jun 2009

See a longer list of these articles.

Technical information about 'Purkinje Cells'

Definition: The output neurons of the cerebellar cortex.

Descriptor UI: D011689

Alternative terms: Purkinje Cells; Cells, Purkinje;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.132.810.428.200.212.600; A08.186.211.865.428.200.212.600; A08.663.784; A11.671.784;

History Note: 65(64)

Technical Notes: in cerebellum: do not confuse with PURKINJE FIBERS (heart)