Purkinje Cells
Research News and Information

Saturday, November 21, 2009

AnkyrinG is required to maintain axo-dendritic polarity in vivo.

22 Sep 2009 Neurons are highly polarized cells that extend a single axon and several dendrites. Studies with cultured neurons indicate that the proximal portion of the axon, denoted as the axon initial segment (AIS), maintains neuronal polarity in vitro. The ... Read more...

Automated analysis of cellular signals from large-scale calcium imaging data.

22 Sep 2009 Recent advances in fluorescence imaging permit studies of Ca(2+) dynamics in large numbers of cells, in anesthetized and awake behaving animals. However, unlike for electrophysiological signals, standardized algorithms for assigning optically ... Read more...

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice.

12 Sep 2009 The dynamin-related guanosine triphosphatase Drp1 mediates the division of mitochondria and peroxisomes. To understand the in vivo function of Drp1, complete and tissue-specific mouse knockouts of Drp1 were generated. Drp1-null mice die by embryonic ... Read more...

Latest indexed articles for 'Purkinje Cells'

These are the very latest articles for this heading:

• AnkyrinG is required to maintain axo-dendritic polarity in vivo. 22 Sep 2009
• Automated analysis of cellular signals from large-scale calcium imaging data. 22 Sep 2009
• The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. 12 Sep 2009
• The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice. 2 Sep 2009
• Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum. 2 Sep 2009
• The p62 antibody reveals various cytoplasmic protein aggregates in spinocerebellar ataxia type 6. 30 Aug 2009
• Differential expression of TrkB isoforms switches climbing fiber-Purkinje cell synaptogenesis to selective synapse elimination. 30 Aug 2009
• Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. 24 Aug 2009
• Reliable coding emerges from coactivation of climbing fibers in microbands of cerebellar Purkinje neurons. 24 Aug 2009
• Elimination of climbing fiber instructive signals during motor learning. 14 Aug 2009
• Glycinergic projection neurons of the cerebellum. 10 Aug 2009
• Ca currents activated by spontaneous firing and synaptic disinhibition in neurons of the cerebellar nuclei. 3 Aug 2009
• Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. 3 Aug 2009
• Synapse elimination in olivo-cerebellar explants occurs during a critical period and leaves an indelible trace in Purkinje cells. Aug 2009
• Late onset cerebellar cortical degeneration in a koala. 30 Jul 2009
• Eyeblink conditioning leads to fewer synapses in the rabbit cerebellar cortex. 30 Jul 2009
• Density of cerebellar basket and stellate cells in autism: evidence for a late developmental loss of Purkinje cells. 30 Jul 2009
• Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. 30 Jul 2009
• Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration. 20 Jul 2009
• Submillisecond optical reporting of membrane potential in situ using a neuronal tracer dye. 20 Jul 2009

See a longer list of these articles.

Technical information about 'Purkinje Cells'

Definition: The output neurons of the cerebellar cortex.

Descriptor UI: D011689

Alternative terms: Purkinje Cells; Cells, Purkinje;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.132.810.428.200.212.600; A08.186.211.865.428.200.212.600; A08.663.784; A11.671.784;

History Note: 65(64)

Technical Notes: in cerebellum: do not confuse with PURKINJE FIBERS (heart)