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Pyridoxine - Therapeutic use
Research News and Information
Definition of 'Pyridoxine'The 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). |
Monday, November 23, 2009
Pyridoxine-dependent seizures: 10-year follow-up of eight cases.
29 Jun 2009 
Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly ... Read more...
Folinic acid-responsive seizures are identical to pyridoxine-dependent epilepsy.
29 Apr 2009 OBJECTIVE: Folinic acid-responsive seizures and pyridoxine-dependent epilepsy are two treatable causes of neonatal epileptic encephalopathy. The former is diagnosed by characteristic peaks on cerebrospinal fluid (CSF) monoamine metabolite analysis; ... Read more...
29 Apr 2009 OBJECTIVES: To investigate whether vascular care slows dementia progression in patients with Alzheimer's disease with cerebrovascular lesions on neuroimaging. DESIGN: Multicenter randomized controlled clinical trial with 2-year follow-up. SETTING: ... Read more...
Latest indexed articles for 'Pyridoxine - Therapeutic use'
These are the very latest articles for this heading:
- Development of a pharmacist-managed latent tuberculosis clinic.
30 Aug 2009 - Pyridoxine-dependent seizures: 10-year follow-up of eight cases. 29 Jun 2009
- Vincristine induced unilateral ptosis. 30 May 2009
- Folinic acid-responsive seizures are identical to pyridoxine-dependent epilepsy. 29 Apr 2009
- Vascular care in patients with Alzheimer's disease with cerebrovascular lesions-a randomized clinical trial. 29 Apr 2009
- Long-term neurodevelopment of children exposed to maternal nausea and vomiting of pregnancy and diclectin. 22 Apr 2009
- Two novel ALDH7A1 (antiquitin) splicing mutations associated with pyridoxine-dependent seizures. 30 Mar 2009
- Pyridoxine-dependent epilepsy: normal outcome in a patient with late diagnosis after prolonged status epilepticus causing cortical blindness. 15 Mar 2009
- Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study. 21 Feb 2009
- The primary hyperoxalurias. 16 Feb 2009
- Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals. 30 Jan 2009
- Thoracic spine compression fracture during isoniazid-induced seizures: case report. 29 Nov 2008
- Homocysteine and depression in later life. 30 Oct 2008
- Wilson disease as a cause of liver injury in cystic fibrosis. 21 Oct 2008
- Prevalence of ALDH7A1 mutations in 18 North American pyridoxine-dependent seizure (PDS) patients. 12 Oct 2008
- Pyridoxine-dependent seizures caused by alpha amino adipic semialdehyde dehydrogenase deficiency: the first polish case with confirmed biochemical and molecular pathology. 12 Oct 2008
- Very-late-onset pyridoxine-dependent seizures not linking to the known 5q31 locus. 29 Sep 2008
- Coma caused by isoniazid poisoning in a patient treated with pyridoxine and hemodialysis. 29 Sep 2008
- Clinical features and the management of pyridoxine-dependent and pyridoxine-responsive seizures: review of 63 North American cases submitted to a patient registry. 31 Aug 2008
- Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. 19 Jul 2008
See a longer list of these articles.
Technical information about 'Pyridoxine'
Definition: The 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
Chemical name: 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-
Registry Number: 65-23-6
Descriptor UI: D011736
Alternative terms: Pyridoxine; Pyridoxol; Pyridoxin; Rodex; Pyridoxine Hydrochloride; Pyridoxol Hydrochloride;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Pharmacological Action: Vitamin B Complex;
Tree Number: D03.383.725.676.925.875;
Technical Notes: deficiency: coordinate PYRIDOXINE /defic (IM) with VITAMIN B 6 DEFICIENCY (IM)