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Radioimmunoassay
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Definition of 'Radioimmunoassay'

Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.

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Sunday, November 22, 2009

Adequacy of vitamin D replacement in severe deficiency is dependent on body mass index.

30 Oct 2009 BACKGROUND: Obesity is associated with hypovitaminosis D. Whether body mass index (BMI) determines the replacement dose of vitamin D to achieve sufficiency is unclear. OBJECTIVE: To determine the relationship between BMI and serum 25-OH vitamin D ... Read more...


Natural history of markers of collagen turnover in patients with early diastolic dysfunction and impact of eplerenone.

25 Oct 2009 OBJECTIVES: This study was designed to evaluate the impact of eplerenone on collagen turnover in preserved systolic function heart failure (HFPSF). BACKGROUND: Despite growing interest in abnormal collagen metabolism as a feature of HFPSF with ... Read more...


Exaggerated response of a vasopressin-enhanced green fluorescent protein transgene to nociceptive stimulation in the rat.

19 Oct 2009 Nociceptive stimulation elicits neuroendocrine responses such as arginine vasopressin (AVP) release as well as activation of the hypothalamo-pituitary-adrenal axis. We have generated novel transgenic rats expressing an AVP-enhanced green fluorescent ... Read more...

 

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Technical information about 'Radioimmunoassay'

Definition: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.

Descriptor UI: D011863

Alternative terms: Radioimmunoassay; Radioimmunoassays;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E01.370.384.700; E01.450.495.410.700; E05.478.594.410.639; E05.601.495.639;

History Note: 68

Technical Notes: NIM; coord with substance /anal or body fluid qualif but not /immunol; do not confuse with IMMUNORADIOMETRIC ASSAY

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