Raphe Nuclei - Drug effects
Research News and Information

Sunday, November 22, 2009

Corticotropin-releasing factor receptor antagonism within the dorsal raphe nucleus reduces social anxiety-like behavior after early-life social isolation.

10 Aug 2009 Social isolation of rats during the early part of development increases social anxiety-like behavior in adulthood. Furthermore, early-life social isolation increases the levels of corticotropin-releasing factor (CRF) receptors in the serotonergic ... Read more...

Opioid mu-receptors in medullary raphe region affect the hypoxic ventilation in anesthetized rats.

22 Jul 2009 Opioids can attenuate the peripheral chemoreceptor-mediated hypoxic ventilatory response (HVR) by acting on central mu-type opioid receptors. Since the medullary raphe region (MRR) expresses abundant mu-receptors and participates in modulating HVR, ... Read more...

Endocannabinoids suppress excitatory synaptic transmission to dorsal raphe serotonin neurons through the activation of presynaptic CB1 receptors.

8 Jul 2009 Endocannabinoid signaling in the dorsal raphe (DR) has recently been implicated in the regulation of anxiety and depression. However, the cellular mechanisms by which endocannabinoids (eCBs) regulate the excitability of DR 5-hydroxytryptamine ... Read more...

Latest indexed articles for 'Raphe Nuclei - Drug effects'

These are the very latest articles for this heading:

• Corticotropin-releasing factor receptor antagonism within the dorsal raphe nucleus reduces social anxiety-like behavior after early-life social isolation. 10 Aug 2009
• Opioid mu-receptors in medullary raphe region affect the hypoxic ventilation in anesthetized rats. 22 Jul 2009
• Endocannabinoids suppress excitatory synaptic transmission to dorsal raphe serotonin neurons through the activation of presynaptic CB1 receptors. 8 Jul 2009
• Glucocorticoid status affects antidepressant regulation of locus coeruleus tyrosine hydroxylase and dorsal raphé tryptophan hydroxylase gene expression. Jul 2009
• [Local GABA-ergic modulation of serotonergic neuron activity in the nucleus raphe magnus] 29 Jun 2009
• The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats. 29 Jun 2009
• Glutamate receptor antagonist infused into the hypothalamic suprachiasmatic nuclei interferes with the diurnal fluctuations in plasma prolactin and corticosterone levels and injected into the mesencephalic dorsal raphe nucleus attenuates the suckling stimulus-induced release of prolactin of the rat. 15 Jun 2009
• Serotonergic mechanisms of the median raphe nucleus-dorsal hippocampus in conditioned fear: Output circuit involves the prefrontal cortex and amygdala. 19 May 2009
• Apamin increases 5-HT cell firing in raphe dorsalis and extracellular 5-HT levels in amygdala: a concomitant in vivo study in anesthetized rats. 12 May 2009
• Chronic citalopram treatment elevates serotonin synthesis in flinders sensitive and flinders resistant lines of rats, with no significant effect on Sprague-Dawley rats. 29 Apr 2009
• Inhibition of serotonin outflow by nociceptin/orphaninFQ in dorsal raphe nucleus slices from normal and stressed rats: Role of corticotropin releasing factor. 29 Apr 2009
• Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex. 7 Apr 2009
• Memory time-course: mRNA 5-HT1A and 5-HT7 receptors. 26 Mar 2009
• Role of the 5-HT(1A) somatodendritic autoreceptor in the dorsal raphe nucleus on salt satiety signaling in rats. 24 Mar 2009
• Acoustic stimulation in vivo and corticotropin-releasing factor in vitro increase tryptophan hydroxylase activity in the rat caudal dorsal raphe nucleus. 12 Mar 2009
• Effects on sleep of melanin-concentrating hormone (MCH) microinjections into the dorsal raphe nucleus. 18 Feb 2009
• Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice. 16 Feb 2009
• Inhibition of monoamine oxidases desensitizes 5-HT1A autoreceptors and allows nicotine to induce a neurochemical and behavioral sensitization. 26 Jan 2009
• 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus. 12 Jan 2009
• Chronic 13-cis-retinoic acid administration disrupts network interactions between the raphe nuclei and the hippocampal system in young adult mice. 8 Jan 2009

See a longer list of these articles.

Technical information about 'Raphe Nuclei'

Definition: Collections of small neurons centrally scattered among many fibers from the level of the trochlear nucleus in the midbrain to the hypoglossal area in the medulla oblongata.

Descriptor UI: D011903

Alternative terms: Raphe Nuclei; Nuclei, Raphe; Nucleus, Raphe; Raphe Nucleus;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.132.659.632; A08.186.211.132.810.507; A08.186.211.653.632; A08.186.211.865.507;

History Note: 85(78); was see under BRAIN STEM 1978-84