Rats, Inbred BB
Research News and Information

Sunday, November 22, 2009

Remodeling rodent models to mimic human type 1 diabetes.

30 Jul 2009 Type 1 diabetes (T1D) occurs when the immune system attacks the insulin-producing beta cells located in the islets of Langerhans within the pancreas. Animal models have played a prominent role in developing an understanding of this disease process, ... Read more...

Recombinant human platelet-derived growth factor BB (rhPDGF-BB) and beta-tricalcium phosphate/collagen matrix enhance fracture healing in a diabetic rat model.

30 Jul 2009 Diabetes mellitus is a common systemic disease that has been associated with poor fracture healing outcomes. The mechanism through which diabetes impairs bone regeneration is unknown. One possible mechanism may be related to either decreased or ... Read more...

Osteogenic and adipogenic differentiation of rat bone marrow cells on non-mulberry and mulberry silk gland fibroin 3D scaffolds.

Jul 2009 This study investigates the potential of 3D silk scaffolds fabricated using tropical tasar non-mulberry, Antheraea mylitta and mulberry, Bombyx mori silk gland fibroin proteins as substrate for osteogenic and adipogenic differentiation of rat bone ... Read more...

Latest indexed articles for 'Rats, Inbred BB'

These are the very latest articles for this heading:

• Remodeling rodent models to mimic human type 1 diabetes. 30 Jul 2009
• Recombinant human platelet-derived growth factor BB (rhPDGF-BB) and beta-tricalcium phosphate/collagen matrix enhance fracture healing in a diabetic rat model. 30 Jul 2009
• Osteogenic and adipogenic differentiation of rat bone marrow cells on non-mulberry and mulberry silk gland fibroin 3D scaffolds. Jul 2009
• S- and C-nucleosidoquinazoline as new nucleoside analogs with potential analgesic and anti-inflammatory activity. 26 May 2009
• Sequence variation and expression of the Gimap gene family in the BB rat. May 2009
• Cardiac ischemia and reperfusion in spontaneously diabetic rats with and without application of EGb 761: II. Interstitium and microvasculature. 29 Apr 2009
• Prevention of diabetes by a hydrolysed casein-based diet in diabetes-prone BioBreeding rats does not involve restoration of the defective natural regulatory T cell function. 23 Apr 2009
• Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes. 6 Apr 2009
• DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes. 24 Mar 2009
• AEB-071 has minimal impact on onset of autoimmune diabetes in NOD mice. 27 Feb 2009
• The role of Toll-like receptor pathways in the mechanism of type 1 diabetes. 30 Jan 2009
• Role of innate immunity in triggering and tuning of autoimmune diabetes. 30 Jan 2009
• Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB rats. 30 Jan 2009
• Neuroprotective role of heme-oxygenase 1 against iodoacetate-induced toxicity in rat cerebellar granule neurons: Role of bilirubin. 26 Jan 2009
• Type 1 diabetes in the BB rat: a polygenic disease. 21 Jan 2009
• Dipyridamole inhibits intracellular calcium transients in isolated rat arteriole smooth muscle cells. 29 Nov 2008
• Innate immune pathways in virus-induced autoimmune diabetes. 29 Nov 2008
• Proteomic changes associated with diabetes in the BB-DP rat. 2 Nov 2008
• Different role of isoproterenol and NOS inhibitors on salivary ducts of rats. 30 Oct 2008
• Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts. 26 Oct 2008

See a longer list of these articles.

Technical information about 'Rats, Inbred BB'

Definition: A strain of Rattus norvegicus which is a model for spontaneous insulin-dependent diabetes mellitus (DIABETES MELLITUS, INSULIN-DEPENDENT).

Descriptor UI: D011913

Alternative terms: Rats, Inbred BB; BB Rat, Inbred; BB Rats, Inbred; Inbred BB Rat; Inbred BB Rats; Rat, Inbred BB; Rats, BB; BB Rat; BB Rats; Rat, BB; BB Wistar Rats; Rats, BB Wistar; Wistar Rats, BB; Bio-Breeding Inbred Rats; Bio Breeding Inbred Rats; Bio-Breeding Inbred Rat; Inbred Rat, Bio-Breeding; Inbred Rats, Bio-Breeding; Rat, Bio-Breeding Inbred; Rats, Bio-Breeding Inbred;

Allowable Qualifiers: abnormalities; anatomy & histology; blood; cerebrospinal fluid; classification; embryology; genetics; growth & development; immunology; injuries; metabolism; microbiology; parasitology; physiology; psychology; surgery; urine; virology;

Tree Number: B01.050.157.760.090; B01.050.199.520.760.090; B01.150.900.649.865.635.505.700.400.090;

History Note: 91(86); was see under RATS, INBRED STRAINS 1986-90

Technical Notes: a model for DIABETES MELLITUS, INSULIN-DEPENDENT; do not confuse with RATS, BRATTLEBORO; NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag RATS