Rats, Inbred Strains
Research News and Information

Tuesday, November 24, 2009

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.

29 Nov 2009 The goal of the investigation was to test the hypothesis that the phosphoinositide-3 kinase (PI3K)/AKT signaling pathway regulates the expression of the major extracellular matrix component of the intervertebral disc, aggrecan, in nucleus pulposus ... Read more...

Inhibition of HIF-1alpha activity by BP-1 ameliorates adjuvant induced arthritis in rats.

16 Sep 2009 Rheumatoid arthritis (RA) is a chronic inflammatory, angiogenic disease. Inflamed synovitis is a hallmark of RA which is hypoxic in nature. Vascular endothelial growth factor (VEGF), one of the key regulators of angiogenesis, is overexpressed in the ... Read more...

Latest indexed articles for 'Rats, Inbred Strains'

These are the very latest articles for this heading:

• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. 29 Nov 2009
• Inhibition of HIF-1alpha activity by BP-1 ameliorates adjuvant induced arthritis in rats. 16 Sep 2009
• The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes. 19 Aug 2009
• Expression of the electrogenic Na+-HCO3--cotransporter NBCe1 in tumoral insulin-producing BRIN-BD11 cells. Aug 2009
• Pharmacological preconditioning in type 2 diabetic rat hearts: the roles of mitochondrial ATP-sensitive potassium channels and the phosphatidylinositol 3-kinase-Akt pathway. 30 Jul 2009
• Synthesis and anti-inflammatory activity of novel (4-hydroxyphenyl)(2,4-dimethoxyphenyl) methanone derivatives. 30 Jul 2009
• Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells. 19 Jul 2009
• Small interfering RNA targeting CD81 ameliorated arthritis in rats. 2 Jul 2009
• Ranking candidate genes in rat models of type 2 diabetes. Jul 2009
• [Effect of early postnatal hypoxia on Wistar and August rats] 29 Jun 2009
• Genome-wide association study of alcohol dependence. 29 Jun 2009
• Anxiety-induced cognitive bias in non-human animals. 24 Jun 2009
• Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation. 21 Jun 2009
• Mechanisms underlying enhanced vasorelaxant response to protease-activated receptor 2-activating peptide in type 2 diabetic Goto-Kakizaki rat mesenteric artery. 19 Jun 2009
• Properties of glycine receptors underlying synaptic currents in presynaptic axon terminals of rod bipolar cells in the rat retina. 13 Jun 2009
• Reversal of high pancreatic islet and white adipose tissue blood flow in type 2 diabetic GK rats by administration of the beta3-adrenoceptor inhibitor SR-59230A. 31 May 2009
• Opportunities and limitations of genetic analysis of hypertensive rat strains. 30 May 2009
• Antileishmaniasis activity of flavonoids from Consolida oliveriana. 30 May 2009
• TLR activation induces TNF-alpha production from adult neural stem/progenitor cells. 30 May 2009

See a longer list of these articles.

Technical information about 'Rats, Inbred Strains'

Definition: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.

Descriptor UI: D011919

Alternative terms: Rats, Inbred Strains; Inbred Strains Rat; Inbred Strains Rats; Rat, Inbred Strains; Inbred Strain of Rats; Rats Inbred Strain; Rats Inbred Strains; Inbred Rat Strains; Inbred Rat Strain; Rat Strain, Inbred; Rat Strains, Inbred; Strain, Inbred Rat; Strains, Inbred Rat; Rat, Inbred Strain; Inbred Strain Rat; Inbred Strain Rats; Rats, Inbred Strain; Strain Rat, Inbred; Strain Rats, Inbred; Inbred Strain of Rat; Rat Inbred Strain; Rat Inbred Strains; Inbred Strains of Rats; August Rats; August Rat; Rat, August; Rats, August;

Allowable Qualifiers: abnormalities; anatomy & histology; blood; cerebrospinal fluid; classification; embryology; genetics; growth & development; immunology; injuries; metabolism; microbiology; parasitology; physiology; psychology; surgery; urine; virology;

Tree Number: B01.050.157.760; B01.050.199.520.760; B01.150.900.649.865.635.505.700.400;

History Note: 72

Technical Notes: GEN or unspecified; prefer specifics; NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag RATS: Manual 18.6.14, 22.36; X ref AUGUST RATS is seen often in Russian lit