Reactive Oxygen Species - Pharmacology
Research News and Information

Sunday, November 22, 2009

Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro.

6 Sep 2009 Resveratrol (3,4',5-trans-trihydroxystilbene) and other hydroxystilbenes exhibit in vitro antioxidant as well as prooxidant effects. The antioxidant properties are assumed to enable these compounds to protect cells from oxidative damage. The ... Read more...

Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species.

12 Aug 2009 Francisella tularensis is an intracellular pathogen whose survival is in part dependent on its ability to resist the microbicidal activity of host-generated reactive oxygen species (ROS) and reactive nitrogen species (RNS). In numerous bacterial ... Read more...

Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.

2 Aug 2009 Identification of the active component and mechanisms of action of traditional medicines is highly desirable. We investigated whether zerumbone, a sesquiterpene from tropical ginger, can enhance the anticancer effects of tumor necrosis ... Read more...

Latest indexed articles for 'Reactive Oxygen Species - Pharmacology'

These are the very latest articles for this heading:

• Comment on "The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation". 29 Sep 2009
• Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro. 6 Sep 2009
• Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species. 12 Aug 2009
• Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species. 2 Aug 2009
• Does botrytis cinerea Ignore H(2)O(2)-induced oxidative stress during infection? Characterization of botrytis activator protein 1. 30 Jul 2009
• Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells. 30 Jul 2009
• Reduced O2 and elevated ROS in sea urchin embryos leads to defects in ectoderm differentiation. 29 Jun 2009
• DAMPs and inflammatory processes: the role of redox in the different outcomes. 27 Jun 2009
• Protective effect of fallopian tubal fluid against activated leucocyte-induced sperm DNA fragmentation: preliminary results. 30 May 2009
• Comparative in vivo and in vitro analyses of putative virulence factors of Burkholderia pseudomallei using lipopolysaccharide, capsule and flagellin mutants. 28 May 2009
• A novel role for vitamin B(12): Cobalamins are intracellular antioxidants in vitro. May 2009
• Acute and chronic modulation of placental chorionic plate artery reactivity by reactive oxygen species. 19 Apr 2009
• Induction of (6-4) photolyase gene transcription by blue light in Xenopus A6 cells. 3 Apr 2009
• Genotoxicity of organoselenium compounds in human leukocytes in vitro. 31 Mar 2009
• Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1. 30 Mar 2009
• [The role of renin-angiotensin system in the pathogenesis of atherosclerosis] 30 Mar 2009
• Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes. 23 Mar 2009
• Discovering genes associated with dormancy in the monogonont rotifer Brachionus plicatilis. 11 Mar 2009
• Arabidopsis GRI is involved in the regulation of cell death induced by extracellular ROS. 9 Mar 2009
• The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa. 8 Mar 2009

See a longer list of these articles.

Technical information about 'Reactive Oxygen Species'

Definition: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.

Registry Number: 0

Descriptor UI: D017382

Alternative terms: Reactive Oxygen Species; Oxygen Species, Reactive; Active Oxygen; Oxygen, Active; Oxygen Radicals; Pro-Oxidants; Pro Oxidants;

Related Mesh Headings: Free Radicals; Oxidative Stress;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D01.339.431; D01.650.775;

History Note: 1993